NSAIDS

Question 1

Which ibuprofen dose is considered high CVD risk?

Answer 1

Ibuprofen 2.4g

Question 2

Which ibuprofen dose is considered low CVD risk?

Answer 2

1.2g

Question 3

What are the high CVD risk drugs?

Answer 3

Ibuprofen 2.4g
Diclofenac
Celecoxib & Etoricoxib (cox 2 selective)

Question 4

what are the low CVD risk NSAIDs?

Answer 4

Naproxen
Ibuprofen 1.2g

Question 5

High risk level in GI side effects?

Answer 5

Prodigal
Ketoprofen
Ketorolac

Question 6

Medium GI side effect risks NSAIDs?

Answer 6

Indometacin
Diclofenav
Naproxen

Question 7

Low Gi side effects risk in NSAIDs

Answer 7

Ibuprofen

Question 8

Which drugs have the lowest GI side effect risks in NSAIDs

Answer 8

Celecoxib & Etoricoxib

( Cox 2 selective inhibitors)

Question 9

NSAIDs and 75mg aspirin risk?

Answer 9

GI bleed risk (only use if necessary)

Question 10

NSAID and alcohol risk?

Answer 10

Increases bleed risk

Question 11

Which pt’s should use PPI for stomach protection?

Answer 11

Elderly over 60/65

Pt taking NSAID

Question 12

NSAIDs and renal impairment?

Answer 12

Avoid in renal impairment

Question 13

Nsaids and pregnancy?

Answer 13

Avoid - risk from 20th week of pregnancy

Question 14

NSAIDS and quinolones?

Answer 14

Increases seizure threshold

AVOID with ciprofloxacin

Question 15

Methotrexate and lithium with NSAID?

Answer 15

Avoid as reduces clearance
Therefore increased toxicity

Question 16

NSAIDS AND AKI?

Answer 16

Avoid

Question 17

MHRA NSAIDs in pregnancy?

Answer 17

Risk to foetal growth with prescribing NSAIDS from 20th week of pregnancy