Gi System 1/2 Flashcards

1
Q

Short bowel syndrome nutritional deficiencies?

A

Vit ADEK, B12

Essential Fatty Acids

Zinc

Selenium

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2
Q

What to treat short bowel syndrome with- diarrhoea and high stomach output?

A

Loperamide and Codeine

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3
Q

Anal fissure symptoms?

A

Tear or ulcer in anal canal so:

Bleeding and pain when pooing

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4
Q

Anal fissure acute treatment?

A

Bulk forming laxatives or Osmotic laxatives

Can also use short term topical such as lidocaine

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5
Q

Pregnancy acute management of anal fissures?

A

DO NOT USE LIDOCAINE

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6
Q

Chronic management of Anal fissure?

A

GTN Rectal if 6 weeks or longer

Topical/oral Diltiazem or Nifedipine
(Low adverse effects)

Specialist: Botox

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7
Q

Haemorrhoids which pain relief to not use?

A

Opioids - cause constipation

NSAIDS - Exacerbate Rectal bleeding

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8
Q

Pregnancy with Haemorrhoid?

A

Bulk forming laxative

Haemorrhoids - HIGH RISK DURING PREGANANCY

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9
Q

Loperamide ages in OTC And RX?

A

OTC: 12yrs+

Rx: 4yrs+

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10
Q

Lopermaide MHRA warning?

A

QT PROLONGATION!!

Serious cardiac reaction with high doses

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11
Q

Loperamide overdose treatment?

A

Naloxone

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12
Q

Loperamide dose?

A

1-2 doses (2-4mg) first then one with every stool Max 8 doses (16mg) per day

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13
Q

IBS non drug treatment?

A
  • Increase exercise
  • Eat reg meals
  • 8 cups of water atleast
  • Avoid sorbitol in diarrhoea
  • Reduce stress/cafeine/alcohol
  • Fresh fruit 3/day
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14
Q

Which laxative to not use in IBS and why?

A

Lactulose - CAUSES BLOATING

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15
Q

If OTC IBS relief doesn’t work what unlicensed other drug can be used?

A

TCA LOW DOSE - Amitriptyline

If TCA doesn’t work —> SSRI

Unlicensed use

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16
Q

Impaired bile formation called what?

A

Cholestasis

17
Q

Cholestatic pruritis treated by?

A
  • Cholestyramine
  • Ursodeoxycholic acid
  • Rifampacin
18
Q

Cholestasis and pregnancy?

When does it occur? Treatment?

A

Usually occurs late pregnancy

Treatment for Pruiritis:
Ursodeoxycholic acid

19
Q

Gallstone left untreated can lead to?

A

Biliary Colic, Cholecystitis, Pancreatitis

20
Q

Gallstone drug treatment? Mild-mod pain? Severe pain?

A

Mild to moderate pain -> Paracetamol/NSAID

SEVERE: IM Diclofenac

21
Q

Exocrine Pancreatitis insufficiency treatment?

A

Pancreatic enzyme replacement (Pancreatin)

22
Q

Pancreatin contains which enzymes?

A

Lipase
Amylase
Protease

23
Q

Why should Pancreatin be taken with food/meals?

A

Prevents early breakdown

24
Q

Pt’s who have both Cystic fibrosis and Pancreatic insufficiency?

A

Fibrosis colonopathy at high does can occur

25
Q

Cystic fibrosis and pancreatic insufficiency maximum dose of lipase daily?

A

Maximum 10,000 units/kg/day

26
Q

What signs or symptoms should be reported in Cystic fibrosis, pancreatic insufficiency pt?

A

New abdominal signs

^^^looking for fibrosing colonopathy

27
Q

Monitor what in pancreatitis insufficiency?

A

Monitor Levels of:
Fat soluble vitamins & Micronutrients

Give supplements when needed

28
Q

Which formulation of drugs should NOT be used in stoma care?

A

MR or Enteric coating

Insufficient effect of drug

Need quick action formulations

29
Q

What can cause diarrhoea, nutrients? (Especially in stoma care)

A
  • Sorbitol
  • Magnesium Antacids
  • Iron (ileostomy)
30
Q

What can cause constipation, Drugs/nutrients? (Especially in stoma care)

A
  • Opioids,
  • Calcium Antacids,
  • Iron (Colostomy)
31
Q

What can cause Gi Irritation, Drugs? (Especially in stoma care)

A

Aspirin + NSAIDS

32
Q

Diuretics/Laxatives can cause dehydration therefore what electrolyte imbalance?

A

Hyperkalaemia

33
Q

Digoxin toxicity can occur in stoma care due to what reason?

A

Hypokalaemia occurring as fluids and Na Depletes

Therefore causing Digoxin Toxicity