MHRA Warnings Flashcards

1
Q

Omega 3 MHRA Warning - which pt to avoid in?

A

Avoid in AF patients as increases risk

Dose: over 1mg tends to be high risk

So counsel 1 1mg od not any more!

Signs: Palpitations, Tachycardia,

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2
Q

Pseudoephedrine MHRA warning?

A

Risk of Encelopathy:

  • Cognitive symptoms: Confusion, headache

-Kidney issues

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3
Q

Finasteride 1mg MHRA warning?

A

Psychiatric disorder or Erectile Dysfunction

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4
Q

Montelukast MHRA warning?

A

Psychiatric side effects - Depressed don’t give

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5
Q

Topiramate MHRA Warning? And can now be used in which condition?

A

PPP - Can lead to cleft

Topirimate can now be used in prophylaxis of migraines

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6
Q

Warfarin and Tramadol interaction MHRA warning?

A

Increases INR thus increases bleeding risk

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7
Q

Epimax ointment MHRA warning?

A

Avoid Eyes and even face - can cause ocular injury!

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8
Q

Fluoriquinol MHRA warning?

A

Avoid unless LAST OPTION then give

Due to QT prolongation - heart effects

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9
Q

Sodium Valproate MHRA?

A

Full pack dispensing

Under 55 year old male/female can’t be given unless two specialists decide

Male pt who may be fathering soon, contraception during treatment and at least 3 months after

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10
Q

Hycoscine Hydrobromide MHRA warning?

A

With Hycoscine Hydrobromide patches - Risk of severe anticholinergic side effects

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11
Q

Nitrofurantoin MHRA warning?

A

Risk of Hepatotoxicity and Pulmonary

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12
Q

Quinolones MHRA warning?

A

Risk of suicidal Thoughts + behaviours

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13
Q

MHRA warnings DOACS?

A

Dose adjustments needed in Renal pts

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14
Q

Febuxostat MHRA warning?

A

Pts with CVD history - Caution

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15
Q

MHRA Methotrexate warning?

A

Photosensitivity - Caution in sun

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16
Q

NSAIDS MHRA warnings?

A

Risk of foetal growth with prescribing from 20th week of pregnancy

17
Q

Isotretinoin MHRA warning?

A

Under 18 must be approved by two prescribers

18
Q

Clozapine MHRA warning?

A

Blood Dyscrasia - Neutropenia low wbc
Agranulocytosis