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PRP2 > CNS - Dementia > Flashcards

CNS - Dementia Flashcards

1
Q

How to alleviate dementia?

A

Increase Acetylcholine

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2
Q

Dementia mild mod treatment?

A

Acetylcholineesterase inhibitors:

Donepezil
Rivastigmine
Galantamine

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3
Q

Donepezil side effects?

A

Neuroleptic malignant syndrome

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4
Q

Rivastigmine side effect?

A

GI SIDE EFFECTS (Transdermal formulation reduces these)

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5
Q

Galantamine side effects?

A

Steven - johnson syndrome

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6
Q

Treatment for mod - severe dementia?

A

Memantine

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7
Q

How can you treat aggravation in pt with dementia?

A

Antipsychotics only

DO NOT USE IN PARKINSONS

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8
Q

Side effects of increasing acetylcholine?

A

Acetylcholine works on Parasympathetic pathways

REST, DIGEST, SECRETE symptoms

Bronchospasm
Bradycardia
Muscle weakness

Diarrhoea

Urinary incontinence
Salivation
Lacrimation (tears flow)
Emesis

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9
Q

Why does inhibiting acetylcholine breakdown enzymes help dementia?

A

By stopping breakdown acetylcholine in brain

It increases, therefore more communication can occur between nerve cells!

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