Musculoskeletal Flashcards

1
Q

Which drug exacerbates gout?

A

Bendroflumethiazides or Chemo drugs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Acute gout treatment?

A

Colchicine 500mg 2-4 times a day
Max 3 days

Not to repeat course within 3 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

NSAIDS interaction with diuretics?

A

NSAIDS induces fluid retention

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Treatment for chronic Gout? 1st line and 2nd line?

A

1st line: Allopurinol

2nd line: Febuxostat

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

MHRA warning with febuxostat?

A

CVD patients contraindicated as increase risk of mortality with history of CVD issues

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Common Allopurinol side effect?

A

Rash - stop and if mild restart carefully

If it recur discontinue immediately

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Allopurinol interacts with?

A

Azathioprine & Mercatopurine

Reduce dose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Nocturnal leg cramps treatment?

A

Quinine sulfate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Why is quinine not routinely recommended then?

A

Potential toxicity risk

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Trial period for quinine?

A

4 weeks

Stop and assess every 3 months

How well did you know this?
1
Not at all
2
3
4
5
Perfectly