Microbio Week 10 - HIV and AIDS (Exam 3) Flashcards

1
Q

How is HIV transmitted?

A

Blood
Semen
Rectal fluids
Vaginal fluids
Breast milk

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2
Q

What is the chance of HIV infection if exposed via needle stick?

A

0.3%

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3
Q

What is the rank of exposure to HIV?

A

Blood transfusion > anal intercourse > needle sharing > needle stick

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4
Q

20% of new diagnoses of HIV are in __________

A

women

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5
Q

How many people infected with HIV are unaware of their infection?

A

1 in 8

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6
Q

20% of the initial diagnosis of HIV is with a co-diagnosis of AIDS, meaning what?

A

Patient was HIV+ for years before learning their status

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7
Q

The majority of new infections are in MSM, with a disproportionate number in _________ populations

A

minority

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8
Q

Condoms are effective in preventing HIV, but only if used…

A

Every time

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9
Q

T/F: There is no difference in the number of new HIV infections in ‘sometimes’ and ‘never’ used condom groups

A

True

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10
Q

Daily pill that is a combination of two HIV drugs used to treat HIV (two NRTI) or a long-acting
injectable

A

PrEP

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11
Q

How often do you need to be tested for HIV while taking PrEP?

A

Every 3 months for pill
Every 2 month for injectable

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12
Q

Why is it necessary to test HIV before and while taking PrEP?

A

You can’t treat an infected person with just 1 class of HIV drugs, resistance will likely develop

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13
Q

T/F: In studies with discordant couples (one partner is living with HIV, and the other partner is not), where the cART treated partner with HIV has undetectable virus levels, there is no transmission to the HIV negative partner even in the absence of condom use

A

True

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14
Q

If you had an exposure to HIV, how soon should you start treatment?

A

ASAP

(absolute best is within 2 hours, but should be started within 72 hours)

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15
Q

If you had an exposure to HIV, how long should you take the ART drugs?

A

28 days

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16
Q

Transmission of HIV from mother to baby occurs in _____% of cases without treatment.

A

25

17
Q

When all recommendations are followed, the transmission of HIV from mother to baby is less than ____%

A

1

18
Q

Does the baby also have to treated after birth if their mother has HIV during pregnancy?

A

YES

19
Q

The time from infection until the time most everyone will show up positive (>99%)

A

Window period

20
Q

What does the lower number in the window range mean?

A

Most people will become + if infected

21
Q

What does the higher number in the window range mean?

A

Almost 100% of people will become + if infected

22
Q

How do you ensure the HIV test is a true negative?

A

Exposure has to be before the higher of the 2 numbers

23
Q

Most people show up HIV+ by 3 weeks, but a small percentage will not show up positive for 3 months. What does this mean?

A

Window period is 3-12 weeks

24
Q

Newer antigen/antibody tests have a shorter window period, from _____ days to _____ days

A

18; 45

25
Q

The nucleic acid test detects exposure the most rapidly, with a window period of _____ days to ____ days

A

10; 33

26
Q

T/F: Positive HIV test results do not need to be confirmed

A

FALSE, they must be confirmed because there can be false positives