mechanical components of muscle fiber/ action potentials Flashcards

1
Q

two mechanical components

A

myofibrils and myofilaments

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2
Q

myofibrils

A

protein filaments long thread like structure that extend entire end of muscle fiber
made up of sacromeres put together

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3
Q

sacromeres

A

functional and structural unit of muscle cell
smallest part that can contract
made of myofilaments

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4
Q

z disks

A

filamentous network protein that serves as attachment site for actin (thin) filament in sarcomere

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5
Q

region of sacromere (I band)

A

lighter stained
cotains z disk and extends to ends of mysoin filament

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6
Q

region of sacromere ( A bands)

A

dark stained
overlaping myosin and actin (except at center)

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7
Q

region of sacromere (h zone)

A

area in a band where myosin and actin do not overlap

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8
Q

M line
region of sacromere

A

mdille of h zone—delicate fliaments holding myosin in place

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9
Q

Actin Filament

A

thin filament
attach at either end of sacromere
two strands of fibrous actin to form double helix

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10
Q

three parts of actin filament

A

G-actin
Troponin
Tropomyosin

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11
Q

G actin
(actin flimanet)

A

has active site for myosin head bonding during muscle contraction

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12
Q

Tropomyosin
(of actin)

A

protein that lies in grove of fibrous actin strand
when relaxed cover G actin binding sites
cannot contract until uncovers site

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13
Q

Troponin
(of actin)

A

consists of 3 subunits
1. anchors troponin to actin
2. prevents tropomyosin from uncovering G site
3. Binds to calcium

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14
Q

Tropomyosin/Troponin complex regulates interaction between G site and myosin T/F

A

True

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15
Q

Myosin filament

A

thick filament
composed of myosin heavy chains to form rod and two myosin heads
look like golf club

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16
Q

Myosin head functions (3)

A
  1. can bind to active sites on G actin of Actin
  2. attach to rod portion by hinge that can bend during contraction
  3. are ATPase enzymes and actively breakdown ATP and release energy–part used to bend during contraction
17
Q

when muscle contracts- what happens to the length of mysoin and actin filaments

A

stays the same

18
Q

when muscle contracts what happens to the a zone

A

stays the same

19
Q

when muscle contracts what happens to the H zone

A

disappears

20
Q

resting membrane potential

A

charge of membrane at rest
inside of cell more negative at rest and outside more positive
ensured by NaK pump

21
Q

inside of cell more negative because

A

cumulation of large negative protein molecules
more K on inside than on outside

22
Q

outside of cell more postive bc

A

more Na on outside of cell than on inside

23
Q

NaK pump

A

for every three Na pumped out 2 K are pumped in

24
Q

depolarization

A

inside of plasma membrane becomes more positive (less negative) if change reaches THRESHOLD action potential triggered

25
Q

threshold

A

voltage gated Na channels open

26
Q

further depolrization

A

positive Na is rushed into the cell ; inside cell becomes more mostive

27
Q

repolarization

A

return of normal resting potential
originally drops lower than normal than rebounds
voltage gated K channels open and K is rushed into the cell

28
Q

All or nothing principle

A

all action potentials identical for a given excitable cell
if stimulus strong enough to reach threshold, all changes made without stopping
if not strong enough, no action potential produced

29
Q

propagate

A

action potential ant one spot stimulates action potential at next spot like dominoes

30
Q

action potential frequency

A

number of action potentials produced per unit of time
strong stimulus causes more action potentials