bone cells Flashcards
osteochondroal progenitor cells
stem cells that differentiate into chondroblasts/osteoblasts
location of osteochondral progenitor cells
inner layer of perichondrium
perisotium
endosteum
Chondroblasts
secrete cartilage matrix
derived from osteochondroal progenitor cells
chondrocytes
Differentiated Chondroblasts once done secreted matrix
housed in lacunae
osteoBLASTS
bone building cells by ossification
derived from osteochondral progenitor cells
osteoblasts secrete
collagen and protoglycans,
matrix vesicles which form hydroproxipate
ossification
formation of new bone
occurs through appostional growth
osteoblasts connect to other osteoblasts through gap junctions
ossification
formation of new bone
occurs through appostional growth
osteoblasts connect to other osteoblasts through gap junctions
Osteocytes
mature bone cells
very long lived
derived from osteoblasts
osteoCYTES receive nutrition by
diffusion from small amount of fluid in lacunae that travels through canliculi and gap junctions
osteoCLASTS
reabsorption of bones
massive multinucleated cells
osteoclasts derived from
red bone marrow that also makes monocytes
osteoclasts derived from
red bone marrow that also makes monocytes
osteoclasts bone reabsorption process
- plasma membrane becomes ruffled border
2.ATP powered H+ pumps and protien enzymes fuse with border - secretion of H+ makes environment acidic and breakdown bone matrix
- proteins digest organic materials
- products carried across cytoplasm of osteoclasts through transcytosis and deposited on other sdie