heart development Flashcards
the cardiovascular system is the _____ major organ system to function in the embryo at the _____
-first
-end of week 3
what is the origin of blood vessels
blood islands: mesodermal mesenchyme cells, gives rise to blood cells, vessels and the heart
-collect at the cranial end
middle end of W3:
-day 20:
the embryonic heart reaches the thorax and isa pair of endothelial tubes in the body midline
-the tubes fuse together and pushes blood out of both ends.
-all four chambers arise from tubes
day 22:
heart starts pumping
-4 buldges have dev along the heart tube: sinus venosus, atrium, ventricle, bulbus cordis
sinus venosus
initially receives all blood from the veins of the embryo
-becomes: smooth walled part of the right atrium, coronary sinus, and the SA node, also the posterior wall of left atrium
-collects deox blood
atrium
gives rise to pectinate muscles of right and left atria
ventricle:
strongest pumping chamber
-becomes the left ventricle
bulbus cordis and truncus arteriosis (cranial extension)
gives rise to the right ventricle, pulmonary trunk, and first part of the aorta
when does bending of the heart occur and why
days 23-28
-rapid growth of ventricle and bulbus cordis cause bending
bending
what direction do the ventricle and atrium move
-s shape
-ventricle: caudally
-atrium
-cranially
result of cardiac looping
the heart fold on itself and assumes its normal position of the left part of the thorax with atria: posteriorly and ventricles: anterior
by month 2
the heart divides into a series of chambers by formation of midline atrial and ventricular septa and valves
month 2
endocardial cushions
help form the hearts midline septum and valves
month 2
interatrial septum
forms by growing caudally from the hearts roof
month 2
interventricular septum
grows cranially from the hearts apex
month 2
neural crest cells
migrate where the atrium meets ventricle and make valves, base of pulmonary trunk, and descending aorta