Gross Reproductive Pathology Flashcards
What are the 3 major categories of sexual development disorders?
Normal male karyotype (XY) disorder
Normal female Karotype (XX) disorder
Abnormal or missing sex chromosome disorder
What is persistent mullerian duct syndrome?
Normal male karyotype (XY) disorder
there is XY chromosome, male karyotype and uterus, is a condition of Minature Schnauzers.
Polled syndrome of goats, which present with an XX karyotype with testes, is an example of which repro disorder category?
normal female Karyotype XX disorder
Freemartin calves (chimeras) are an example of what category of reproductive disorder?
abnormal or missing sex chromosome disorder
What is an appropriate description ?
What is your morphologicla diagnosis?
Here we have a bulging, pink neoplasm that compressed adjacent normal tissue.
This is an example of a testicular seminoma.
Evaluate this image to decide the tumour present
This tumour is an example of an interstitial cell tumour. This could also be known as a Leydig cell tumour.
The Leydig cell is the primary source of testosterone and so has a vital role in physiological processes. Leydig cell tumours often secrete excess androgens
What is the diagnosis of this testicular mass sample?
testicular seminoma
What is the diagnosis of this testicular mass sample?
Leydig cell tumour
What type of bacteria is Brucella ovis?
A Gram-negative coccobacillus.
What is the primary economic impact of Brucella ovis infection in rams?
It causes epididymitis and reduced fertility.
How long can an infected ram shed Brucella ovis?
2-4 years or longer, mainly in semen and urine.
Can a ram be infected with Brucella ovis without showing clinical signs?
Yes, an infected ram may appear clinically normal while shedding the bacteria.
What is the primary route of Brucella ovis transmission?
Sexual transmission through ram-to-ram mounting.
Can Brucella ovis be transmitted through contaminated pastures?
No, field studies show sheep grazing contaminated pastures do not become infected.
Can Brucella ovis spread through urine?
Yes, but semen is the main source of transmission.
What are the main anatomical structures affected by Brucella ovis?
The epididymis, tunica vaginalis, and testis.
Which part of the epididymis is most commonly affected by Brucella ovis?
The tail of the epididymis is affected more often than the head or body.
What type of fluid-filled structures may develop in the epididymis due to Brucella ovis?
Spermatoceles, containing inspissated spermatic fluid.
What changes occur in the tunica vaginalis due to Brucella ovis infection?
It becomes thickened and fibrotic, and extensive adhesions may form.
What effect does Brucella ovis have on the testis?
It can cause fibrous atrophy of the testis.
What is the best way to prevent Brucella ovis spread in a flock?
Testing and culling infected rams, as well as avoiding ram-to-ram mounting.
What is your morphological diagnosis?
Given the H&E image, what is the aetiology/cause ?
This is the testis. Here we see ‘epididymitis’ which is focally extensive, being classified as moderate and acute.
From the H& E image we can see the cause is Brucella Ovis.
What tissues/organs are present?
What is your morphological diagnosis?
Here we are looking at the urinary bladder and the prostate.
What can be seen is that the prostate has undergone hyperplasia, it would be described as diffuse, severe and chronic.
