Differential diagnoses for Cutaneous & Subcutaneous masses Flashcards by Leah Stevenart

Q

A

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Q

Give examples of epithelial skin tumours

A

Trichoblastoma (basal cell tumour)

Trichoepithelioma (hair follicle tumour)

Squamous cell carcinoma

Sebaceous cell tumours (adenoma, carcinoma, epithelioma)

Anal sac apocrine adenocarcinoma

Perianal gland (hepatoid) adenoma

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Q

Describe mesenchymal skin tumours

A

Arise from connective tissue, muscle, bone and cartilage, nerves, endothelial cells
Cells in non-cohesive aggregates or individually
Cell borders are variably defined and often indistinct
Embedded in matrix
Spindle shaped cells with cytoplasmic tails common
Cells can be oval or plump

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Q

Describe the features of a lipoma

A

Adipocytes with small nucleus and abundant (single vacuole/globule) cytoplasm
Free Fatty droplets
Identical to subcut fat

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Q

Give examples of round cell tumours

A

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Q

Describe the features of a round cell tumour

A

Individual cells/not adherent
Roundish cells
High cell harvest

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Q

What is a plasmacytoma?

A

when abnormal plasma cells grow into a tumour in the bone or soft tissue

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Q

Describe the features of a plasmacytoma

A

Discrete cells
Eccentric nuclei
Chromatin clumping
Perinuclear clear zones:
- Golgi, Ig production

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Q

What type of cell is this?

A

Epithelial

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Q

What type of cell is this?

A

round cell

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Q

What type of cell is this?

A

Mesenchymal

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Q

What type of cell tumour is this?

A

Epithelial

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Q

What type of cell tumour is this?

A

Mesenchymal

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Q

Give examples of mesenchymal tumours

A

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Q

What type of cell tumour is this?

A

mesenchymal

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Q

What type of tumour is this?

A

lipoma (mesenchymal)

Q

What type of cell tumour is this?

A

round cell tumour

Q

What type of cell tumour is this?

A

Round cell

Q

What type of cell tumour is this?

A

round cell