Genetics and Phenotypes Flashcards

1
Q

Structure of commercial poultry breeding

A

• Small number of multi-national companies
• In the UK 2 companies supply ~ 90% of broiler
breeding stock
• UK breeding companies for layers – franchisees of international companies
• Rapid rates of genetic progress in ‘pure-bred’ breeding nucleus populations
• Rapid transfer of improvements through ‘breeding pyramid’ to commercial production of crossbred stock

Pure lines ➡️
Great-grand parent
(selection)➡️
Grand parent stock (crossed)➡️
Parent Stock
(2 way cross males and females)➡️
Production stock (4 way cross)
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2
Q

Poultry – Primary Breeding Sector

A
  • Pure lines
  • Relatively small number breeding stock • Produce large number of chicks
  • High selection differentials
  • Typically selecting 1% males and 10% females
  • Low generation intervals
  • High Biosecurity
  • High investment in research
  • Use of measurement technology • Use of genomics
  • Multiplication
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3
Q

Breeding objectives - Layers

A

To obtain maximum number of saleable eggs per hen housed at low feed cost per egg or per kg egg mass and the eggs should have optimal internal and external qualities
• Age at sexual maturity • Rate of lay
• Livability
• Egg weight
• Feed conversion ratio • Albumen height
• Temperament
• Skeletal integrity
• Adaptation to heat stress • Shell colour and strength
• Body weight
More than 30 traits recorded and monitored in
pure-bred populations

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4
Q

Breeding objectives - Broilers

A

Selection on commercial weight in commercial conditions
• Breast muscle weight • Meat quality
• Food Conversion Ratio • Hatchability
• Skeletal integrity
• Metabolic disorders and immune response
• Welfare
1000’s of measurements made – inc electronic feed recording,
CT scanning, bone x rays etc

Selection based on objective criteria

  • Individual EBVs calculated using 1000’s of records
  • EBVs combined into overall Selection Index
  • Each trait weighted in Index
  • Weightings based on
  • Economicimportance
  • Heritability
  • Genetic correlations
  • Required change
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5
Q

Small scale poultry breeding

A
  • 280breedsofpoultrykeptintheUK • 33 duck
  • 23 geese
  • 24 fowls
  • 63miniaturefowls
  • 20truebantamfowls
  • 8 turkeys
  • No pedigree registration
  • No individual identity recording
  • Poultry Club regulates exhibition breeders
  • National Poultry collection – individual pedigree recording
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6
Q

Structure of commercial pig breeding

A

• Multi-national companies
• Rapid rates of genetic progress in ‘pure-bred’
breeding nucleus populations
• Rapid transfer of improvements through ‘breeding pyramid’ to commercial production of crossbred stock
• Biosecurity prioritised
• Integrated production
• Significant investment in research

Pure lines➡️
Grand parent stock➡️
Parent Stock➡️
(Specialist sire and dam lines)➡️
Production stock (Crossbred)
 Or 
Artificial insemination from pure lines to Production stock (Crossbred)
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7
Q

Pigs - Genetic improvement

A
  • Specialised sire and dam lines (proprietary) • Multiple populations of each
  • Index Selection – Performance Testing
  • Measure performance in commercial systems
  • Detailed recording of weight and feed intake • Ultrasonicmeasurementoffatdepth
  • Large nucleus populations – allows high selection differentials • Hyper-prolific selection
  • Marker Assisted Selection
  • Genomic selection
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8
Q

Pigs – Breeding objectives

A
  • Lifetime production
  • Pigsweanedpersowlifetime
  • Feed efficiency
  • Lean %
  • Growth
  • Meat quality
  • Vitality
  • Piglet survival
  • Legstrengthandlocomotion
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9
Q

Small scale pig breeding

A
  • 11 Native Breeds
  • All considered rare and at risk
  • British Pig Association
  • Purebred registration and pedigree services
  • Conservation of rare breeds
  • Gene banking
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10
Q

Dairy cattle breeding

A
  • Bulls – International AI companies/Co-operatives • Cows – Individual herds
  • Progeny testing
  • National breeding programmes
  • Shareinformation
  • Interbull – international evaluations
  • Independent milk recording
  • Widely published genetic evaluations
  • Public or levy funding of research
Elite herds Bulls➡️
Artificial Insemination Companies➡️
   Progeny test➡️
Artificial Insemination➡️
Production herds
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11
Q

Dairy cow Progeny Testing

A

Occurs over 6 years

Top AI bulls and Top cows mated ➡️ Young bulls screened➡️ Test inseminations ➡️ Progeny born ➡️ Daughters mated➡️ Daughters Calve➡️ Daughters complete lactation➡️ Bulls evaluated➡️ Semen sold from best bulls
And then back to Top AI bulls and Top cows mated

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12
Q

Dairy cows Genetic evaluation - PTAs

A
  • Include information from all relatives • Performing in different herds/systems • Expressed relative to average
  • Production traits
  • Milk, Fat, Protein
  • Health, welfare and fitness traits • SCC, Lifespan, Fertility, Locomotion
  • Management traits
  • Temperament,Easeofcalving,
  • Type traits
  • Conformation

Predicted Transmitting Ability
PTA = 1⁄2 EBV

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13
Q

Dairy cows Genetic evaluation - PLI

A
Genetic evaluation - PLI
  Profitable Lifetime Index
• Combines PTAs into one score
• Measures Overall genetic Merit
• Other indexes for specific systems
• Each country has it’s own Indexes 
• E.g. Ireland EBI
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14
Q

Dairy cows Breeds and crossbreeding

A
  • Dominated by Holstein-Friesian
  • Majority ‘pure’
  • Crossbreeding increasing in popularity
  • Genetic evaluation – AHDB
  • Individual breed societies • Pedigree registration
  • Typeassessments
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15
Q

Beef cattle breeding

A
  • Individual pedigree herds
  • Average>80cows
  • Selling 5 breeding bulls per year on average
  • Large number of breeds
  • On farm performance recording
  • Genetic evaluation services provided independently • Nationalevaluations–withinbreed
  • EBVs
  • Terminal sire Index + Self replacing Index
  • Research limited – breed societies

Elite/pedigree herds ➡️ Bulls ➡️
Artificial Insemination Companies➡️ Dairy herds.
Or

Elite/pedigree herds ➡️ Bulls ➡️ Suckler herds
Or

Elite/pedigree herds ➡️ Bulls ➡️
Artificial Insemination Companies➡️ Suckler herds

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16
Q

Beef cattle breeding – traits recorded

A
  • Calving
  • Birth weight
  • Gestation Length
  • Calving Ease
  • Growth and Carcase
  • 200daygrowth
  • 400daygrowth
  • Muscle depth/Eye muscle area
  • Backfat depth
  • Maternal traits
  • 200daymilk
  • Maternal calving ease
  • Ageatfirstcalving
  • Calving interval
17
Q

Beef cattle – data from commercial herds

A
  • British Cattle Movement Service
  • Sire notification on passport
  • Abattoir data can be linked back to sire
  • EBVs available for
  • Agetoslaughter
  • Carcaseweight
  • Carcaseconformation
  • Carcasefatclass
  • Averagedailycarcasegain
  • AHDB National Beef Evaluations
18
Q

Sheep breeding

A
  • Industry – 56% crossbred ewes 44% purebred
  • Individual pedigree flocks
  • Selling breeding rams
  • Very large number of breeds (>100)
  • 62 breeds numerically small
  • On farm performance recording
  • Genetic evaluation services provided independently
  • Nationalevaluations–withinbreed
  • EBVs
  • > 33%ramstradedhaveEBVs
  • Terminalsires>maternalbreeds>hillbreeds
  • Research limited – breed societies

Elite/pedigree flocks rams➡️. Commercial flock

19
Q

Sheep breeding – hill breeds

A
  • Average flock size ~ 300 ewes • Mainly purebred
  • Locallyadapted‘types’
  • Very traditional selection
  • On farm performance recording
  • Difficult to achieve in hill conditions • DNA parentage used in Wales
  • Traits
  • Survival
  • Maternal
  • Growth and Carcase
20
Q

Sheep breeding – maternal breeds

A
  • Commercial flocks – self replacing
  • Greater use of EBVs when purchasing rams
  • On farm performance recording
  • Traits
  • Survival
  • Maternal
  • Growth and Carcase
  • Disease e.g nematode resistance
21
Q

Sheep breeding – crossing breeds

A
• Sires of crossbred ewes
• Purebred numbers small – but important genetic
contribution
• On farm performance recording
• Very limited in BFL and BL – very traditional
• Aberfield – all recorded and sold with EBVs 
• Innovis
• Traits
• Survival
• Maternal
• Growth and Carcase
• Diseasee.gnematoderesistance
22
Q

Sheep breeding – terminal sires

A
  • Small purebred flocks
  • On farm performance recording
  • Extensive use of EBVs
  • Traits
  • Live weight Growth
  • Muscle Depth and Fat Depth
  • Most research has been focussed on Terminal sires
23
Q

EBVs in Dog Breeding

Complex (polygenic) inherited traits

A
  • Inherited disorders
  • Hip and elbow dysplasia
  • Chiari Malformation Syringomyelia (CMSM)(?)
  • Behavioural traits
  • Guide Dogs
24
Q

Recap of Poultry and Pigs breeding

A
  • Breeding pyramid
  • Integrated
  • Objective measures
  • High rates of genetic improvement
  • High selection differentials
  • Short generation intervals
  • Measurement technology
25
Q

Recap of Dairy Cattle breeding

A
• International AI companies
• Bull breeding – highly
organised
• Cow breeding – farm level
• Good rates of genetic improvement
• High selection differentials
• Long generation intervals
• High accuracy of selection
26
Q

Recap of Beef Cattle and Sheep breeding

A
• Limited AI
• Small individual breeding
herds and flocks
• Independent genetic evaluations
• Patchy genetic improvement
• Low selection differentials
• Long generation intervals
• Limited use of EBVs