Gastrulation & Neurulation Flashcards

1
Q

What is Gastrulation?

A

Initiated by organiser, which is in future, dorsal or posterior region

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2
Q

What happens during Gastrulation?

A

Formation of Primitive streak and node in the epiblast, posterior extension of streak

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3
Q

What happens with the Node formed in the epiblast?

A

Migration of epiblast cells through here to form endoderm, anterior notochord and prechordal mesoderm

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4
Q

What happens with the Primitive streak formed?

A

Migration of epiblast cells through here to form ventral and lateral mesoderm

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5
Q

What happens with the streak?

A

Regression and replaced by notochord

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6
Q

What is Neurulation?

A

Formation of neural tube which forms brain and spinal code

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7
Q

What happens to the Organisers in the mesoderm?

A

Forms neural plate in ectoderm which changes in cell shape and surface properties, the neural plate then folds in the hinge regions, the edges of folds fuse, the tube seperate and sinks away from ectoderm

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8
Q

What happens if the edges of the folds of the neural plate dont fuse?

A

Spina bifida, anencephaly

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9
Q

What do clusters of future neural cells do?

A

Form in crests of dorsolaterally to tube to create future nerves and pigment cells

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