Fertilisation To Trilaminar Embryology Flashcards
What receptor does sperm bind to on the ovum
Glycoprotein ZP3 on the zona pellucida
How does the sperm penetrate the zona pellucida
Release o acrosomal enzymes
What are the 3 components of a sperm head
Acrosome
Sperm nucleus (haploid)
Plasma membrane
Why do the plasma membranes of the sperm and ovum need to fuse
So nucleus of sperm can enter
What does the entry of sperm into the ovum trigger
Completion of meiosis 2
Release of cortical granules by oocyte
What is the function of cortical granules
Hardens zona pellucida prevent polyspermate
What is the opening for ovum to enter the uterine tubes called
Uterine abdomen oss
What happens to the overall size of the zygote structure
Doesn’t change, blastomere cells get smaller
What types of cell does up to the 8 cell stage blastomere contain
Totipotent
What is a totipotent cell
Can form any cell type
Embryonic cell
Placental cell
What is mosaicism / mitotic nondisjunction
2 different cell lines with different chromosome compliments
(E.g. if 1 cell divides unevenly where 1 daughter cell has 1 chromo and another has 3, only affects those 2 cells not all cells)
How does compaction of the morula
Confined within zona pellucida
To make max use of space, cells become tighter and form cell junctions
Outer-cells form gap junctions
What happens when outer cells in contact with the zona pellucida form gap junctions
Fluid enters through the zona pellucida
What are the 4 components of the blastocyst
Trophoblas (embryonic part of placenta)
Zona pellucida
Blastocyst cavity
Inner cell mass (forms the embryo)
How does blastocyst hatching occur
Trophoblas broken down
Cell bundles contract to burst out allowing implantation
Where does implantation occur
Directly on the endometrial lining on the superior aspect of the posterior uterine wall
What is the function of the corpus luteum
After ovulation, follicle develops into corpus luteum which secretes progesterone
What is the function of progesterone
Maintain thick endometrial lining for implantation
What are the 2 cell layers of the bilaminar embryo
Epiblast
Hypoblast
Amniotic cavity also begins to form in embryo
What do trophoblast (outer cell mass) develop into
Cytotrophoblast
Syncytiotrophoblast