Exam 2- week 7 ppt 9 Diencephalon Hypothalamus Flashcards
What are the major functions of the hypothalamus? (5)
~Regulates endocrine & autonomic function ~Chief effector of the limbic system ~Body temperature regulation ~Sleep–wakefulness cycles ~Emotional and behavioral functions
Hypothalamus has _ main regions
~Anterior (supraoptic)
~Middle (tuberal)
~Posterior (mammillary)
What is included in anterior nuclei? (5)
~Preoptic nucleus ~Supraoptic nucleus ~Suprachiasmatic nucleus ~Anterior nucleus ~Paraventricular nucleus
What is included in middle nuclei? (5)
~Dorsomedial nucleus ~Ventromedial nucleus ~Arcuate nucleus ~Dorsal hypothalamic ~Lateral hypothalamic areas
What is included in posterior nuclei? (2)
~posterior nucleus
~mammillary nucleus
Neural input into the hypothalamus come primarily from
limbic system
~from the hippocampus from fornix
~from the amygdala via stria terminalis and ventral amygdalofugal pathways (VAF)
~the ventral tegmental area of the midbrain and nucleus accumbens via medial forebrain bundle (MFB)
~from Raphe nuclei & locus coeruleus of brainstem via medial forebrain bundle
~from the Solitary nucleus of medulla via dorsal longitudinal fasciculus
~cicumventricular sensory organs
Heavy input from limbic structures to the hypothalamus suggest a role in
suggests a role of hypothalamus in providing the physiological response to emotion
What are the 3 major cicumventricular sensory organs?
~Area postrema (AP)
~Subfornical organ (SFO)
~Organum vasculosum of lamina terminalis (OVLT)
Role of SFO and OVLT in the hypothalamus
the hypo-thalamic osmoreceptors for ADH release
Role of AP in the hypothalamus
senses toxins which stimulated for vomiting via the hypothalamus’s connections with the dorsal motor nucleus of X
Neural output of the hypothalamus
~cerebral cortex
~midbrain
~hippocampus
~amygdala
~septal nuclei via the same paths as inputs
~Dorsal tegmental fasciculus to spinal autonomic centers
~Thalamus & midbrain via mammillothalamic & mammillotegmental tracts
Anterior region: preoptic nucleus (function)
~Thermal regulation
~Drinking behaviors
~Sleep
Anterior region: supraoptic and paraventricular nucleus (function)
~Water balance
~Milk ejection
~uterine contraction through their connections with the pituitary gland
Anterior region: suprachiasmatic nucleus (function)
~regulation of Circadian rhythms
~circadian release of hormones
Anterior region: paraventricular nucleus (function)
eating behaviors and is know as a Satiety center
Middle region: ventromedial nucleus (function)
~eating behavior
~know as the primary Satiety center
Middle region: dorsomedial nucleus (function)
~eating behavior
~functioning as a hunger center
~physiological responses to Emotional behaviors
Middle region: arcuate nucleus (function)
~eating behavior
~some complex roles in feeding behaviors
Posterior region: Posterior nucleus (function)
~waking and cortical activion
Posterior region: mammillary body nucleus (function)
~memory functions
Hypothalamic syndrome: problems with regulation of
~body temperature ~sleep- wakefulness cycle ~urine production ~eating behavior ~reproduction behaviors
Hypothalamic syndrome: what is damaged to affect body temperature?
~Anterior damage produces hyperthermia
~Posterior damage produces hypothermia
Hypothalamic syndrome: what is damaged to affect sleep?
~wakefulness cycle controlled by suprachiasmatic nucleus
~Anterior damage produces insomnia
~Posterior damage produces hypersomnia
Hypothalamic syndrome: what is damaged to affect urine production?
~Damage to paraventricular or supraoptic nuclei prevent synthesis & release of antidiuretic hormone (ADH)
~Produces “diabetes insipidus” with large output of very dilute urine
Hypothalamic syndrome: what is damaged to affect eating behavior?
~Damage to ventromedial nucleus leads to hyperphagia & obesity
~damage to the dorsomedial nucleus produces starvation
Hypothalamic syndrome: what is damaged to affect reproductive behavior?
~early damages leading to underdevelopment of genitalia
~Froehlich syndrome with antisocial behaviors, unprovoked rage or aggression