Drug antidotes

Question 1

Antidote for acetaminophen

Answer 1

N-acetylcysteine (replenishes glutathione)

Question 2

Antidote for salicylates

Answer 2

NaHCO3 (alkalinize urine), dialysis

Question 3

Antidote for amphetamines (basic)

Answer 3

Nh4Cl (acidify urine)

Question 4

Antidote for acetylcholinesterase inhibitors, organophosphates

Answer 4

Atropine, pralidoxime

Question 5

Antidote for antimuscarinic, anticholinergic agents

Answer 5

Physostigmine salicylate, control hyperthermia

Question 6

Antidote for beta blockers

Answer 6

Glucagon

Question 7

Antidote for digitalis

Answer 7

Normalize K, Lidocaine, anti-digitalis Fab fragments, Mg2+

Question 8

Antidote for Iron

Answer 8

Deferoxamine, deferasirox

Question 9

Antidote for lead

Answer 9

CaEDTA, dimercaprol, succimer, penicillamine

Question 10

Antidote for mercury, arsenic, gold

Answer 10

Dimercaprol (BAL), succimer

Question 11

Antidote for copper, arsenic, gold

Answer 11

penicillamine

Question 12

Antidote for cyanide

Answer 12

Nitrite +thiosulfate, hydroxocobalamin

Question 13

Antidote for methemoglobin

Answer 13

Methylene blue, vit C

Question 14

Antidote for carbon monoxide

Answer 14

100%, hyperbaric O2

Question 15

Antidote for methanol, ethylene glycol (antifreeze)

Answer 15

Fomepizole > ethanol, dialysis

Question 16

Antidote for opioids

Answer 16

Naloxone/naltrexone

Question 17

Antidote for benzodiazepines

Answer 17

Flumazenil

Question 18

Antidote for TCAs

Answer 18

NaHCO3 (plasma alkalinization)

Question 19

Antidote for heparin

Answer 19

Protamine

Question 20

Antidote for Warfarin

Answer 20

Vit K, fresh frozen plasma

Question 21

Antidote for tPA, streptokinase, urokinase

Answer 21

Aminocaproic acid

Question 22

Antidote for theophylline

Answer 22

beta blocker