Auto-antibodies Flashcards by Allen Ruan

Q

anti-ACh receptor

A

Myasthenia gravis

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Q

anti-basement membrane

A

Goodpasture

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Q

anti-cardiolipin, lupus anticoagulant

A

SLE, antiphopholipid syndrome

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Q

anti-centromere

A

Limited scleroderma (CREST syndrome)

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Q

anti-desmoglein

A

Pemphigus vulgaris

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Q

anti-dsDNA, anti-Smith

A

SLE

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Q

anti-glutamate decarboxylase

A

T1DM

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Q

anti-hemidesmosome

A

Bullous pemphigoid

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Q

anti-histone

A

Drug induced lupus

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Q

anti-Jo-1, anti-SRP, anti-Mi-2

A

Polymyositis, dermatomyositis

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Q

anti-microsomal, anti-thyroglobulin

A

Hashimoto’s thyroiditis

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Q

anti-mitochondrial

A

Primary biliary cirrhosis

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Q

anti-nuclear antibodies

A

SLE, nonspecific

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Q

anti-Scl-70 (anti-DNA topoisomerase I)

A

Scleroderma (diffuse)

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Q

anti-smooth muscle

A

Autoimmune hepatitis

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Q

anti-SSA, anti-SSB (anti-Ro, anti-La)

A

Sjogren syndrome

Q

anti-TSH receptor

A

Grave’s disease

Q

anti-U1 RNP

A

Mixed connective tissue disease

Q

c-ANCA (PR3-ANCA)

A

Granulomatosis with polyangiitis (Wegener)

Q

IgA anti-endomysial, IgA anti-tissue transglutaminase

A

Celiac disease

Q

p-ANCA (MPO-ANCA)

A

Microscopic polyangiitis, Churg-Strauss syndrome

Q

Rhematoid factor (IgM specific to IgG Fc region), anti-CCP

A

RA