Cytology clinical midterm 1

Question 1

What is marfan syndrome caused by

Answer 1

• mutation in the fibrillin gene

Question 2

What does defective fibrillin lead to in Marfan syndrome

Answer 2

• Weakend connective tissues
• skeletel abnormalities( long limbs )
• Aortic Anerysms

Question 3

What is keloid caused by?

Answer 3

• Excessive collagen production by fibroblasts during the healing porcess

Question 4

Give historical features of keloids-

Answer 4

• contain a lot of type 1 and 3 collagen
• High density
• invade surrounding tissues

Question 5

What is Edma

Answer 5

• Accumulation of fluid in the interstitial fluid

Question 6

What contributes to edema

Answer 6

• increased capillary permeability( due to infammation or damage)
• increased hydrostatic pressure
  -deceased osmotic pressure( low levels of proteins)
• blocking of lymphatic which drains excess intersitial fluid