Chronic Inflammation 2 Flashcards
What is granulomatous inflammation characterised by?
Granulomas in tissues and organs.
What is granulomatous inflammation stimulated by?
Indigestible antigen.
What do granulomas aggregate?
Epitheloid macrophages in tissues.
What can granulomas contain and surround?
Giant cells
Dead material
What may surround granulomas?
Lymphocytes
What type of hypersensitivity is found in granulomas?
4
What are granulomas comprised of?
Macrophages
What do giant cells contain?
Large cytoplasm and multiple nuclei.
Where is Langhan’s type often found?
Tuberculosis.
What type of cytoplasm does Langhan’s type have?
Large eosinophilic.
What are foreign body types often associated with?
Pyogenic granulation tissue.
How do silicone associated granulomas occur?
Ruptured silicone implants.
What is the featur of Warthin-Finkeldy type granulomas?
Central cluster of nuclei.
What three infections are granulomatous diseases?
Tuberculosis
Leprosy
Syphilis
What infection is caseous necrosis associated with?
Tuberculosis