cholinergic receptors

Question 1

ANS pre-post receptors

Answer 1

nAcHRs

Question 2

ANS parasympathetic effector receptors

Answer 2

mAcHRs

Question 3

nicotinic receptor stucture

Answer 3

ligand-gated ion channels (Na+,K+)
pentameric structures

Question 4

nicotinic receptor types

Answer 4

ganglionic
muscle (motor endplate)
CNS

Question 5

Ganglionic nicotinic receptors

Answer 5

Mostly in pre-post synapse of ANS

Question 6

Muscarinic receptor structures

Answer 6

G protein coupled receptors
1,3,5 are Gq linked
2,4 are Gi linked

Question 7

M1 receptor

Answer 7

Gq linked
slow excitation of ganglia

Question 8

M2 receptor

Answer 8

Gi linked
decrease heart rate and contraction force

Question 9

M3 receptor

Answer 9

Gq linked
-Causes glandular secretion
-Contraction of smooth muscle
-Dilate vasculature via NO release (eyes, lungs, bladder)

Question 10

sympathetic effector NT

Answer 10

Mostly NA
but some has ACh for muscarnic