analgesics Information Flashcards
1
Q
Neuropathic pain
A
Pain from damages to somatosensory nervous system (phantom pain)
2
Q
Chronic pain
A
Outlasts tissue damage and has no purpose
3
Q
inhibitory pain pathways
A
-opioid receptors in descending pathways to dorsal horn
-noradrenergic inhibitory pathway from locus coeruleus to dorsal horn
4
Q
Opioid receptors
A
GPCR Gi/Go linked in brain and spinal cord
5
Q
opioid action sites
A
-specific brain nuclei
-dorsal horn
-periphery at nerve terminals
6
Q
Prostaglandin effect for pain
A
Causes sensitization of nerves to bradykinin and 5-HT pain signals
