Adrenergic receptors Flashcards
adrenergic receptor location
ANS effector organs
Noradrenaline
endogenous transmitter released from synapses
adrenaline
hormone from adrenal medulla
dopamine
NA precursor but endogenous transmitter in CNS
Alpha 1 adrenergic receptor
Gq linked
-Constricts SM except for Gastrointestinal tract
-causes glycogen-lysis (increase metabolism)
Alpha 2 adrenergic receptor
Gi linked
- relax gastrointestinal tract
-depresses further adrenergic and cholinergic releases
Beta 1 adrenergic receptor
Gs linked
-Has strong effect on increasing heart rate and contraction
Beta 2 adrenergic receptor
Gs linked
-relaxes most SM
-causes tremor and muscle mass/ contraction force
-inhibits histamine release
-stimulates further adrenergic release
Beta 3 adrenergic receptor
Gs linked
-relaxes bladder
-increase anabolic metabolism