Cells of the nervous system Flashcards
2 cells that make up nervous system
Neurons
Glial cells
What do Neurons do?
Receive stimuli, conduct action potentials, and transmit signals to other neurons or organs
What do glial cells do
Support and protect neurons
Neurons
electrically excitable cells of the nervous system
3 parts to a neuron
Cell body
2 types of cellular projections
Dendrite
A cellular projection from a neuron with a branching organization
Receiving portion of the neuron - get info from other axons
Axon
Nerve fiber; projection with a straight and uniform diameter
Arises from a cone-shaped area of the neuron cell body called Axon hillock
Parts of an axon
Axon hillock (part of nueron body)
Initial segment (where the axon technically starts)
Trigger zone (Axon hillock + initial segment)
Axoplasm (cytoplasm)
Axolemma (plasma membrane)
Presynaptic terminals (end of the axon)
Neurotransmitters (single molecules found in presynaptic terminals)
Anterograde
the movement away from the cell body
Retrograde
The movement toward the cell body
3 types of neurons, functional classification
Sensory - afferent
Motor - efferent
Interneurons - conduction action potentials from one neuron to another
3 types of neurons, structural classification
Multipolar // many dendrites, single axon
Bipolar // one dendrite adn one axon
Psuedo-unipolar // single process extending from cell body
Functions of glial cells (4)
1) form a protective permeability barrier between the blood & the brain/ spinal cord;
2) phagocytize foreign substances
3) produce cerebrospinal fluid
4) Form myelin sheaths around axons
4 types of Glial cells
1) Astrocytes
2) Ependymal cells
3) Microglia
4) Oligodendrocytes
Astrocytes
Star-shaped glial cells
Regulate the composition of extracellular brain fluid and form the blood-brain barrier
Reactive astrocytosis
A result of most injuries to CNS
Astrocytes wall off the injury site and limit the spread of inflammation to surrounding healthy tissue (good)
Limit regeneration of axons of injured neurons (bad)
Ependymal cells
Cells that line the ventricles of the brain and central canal of the spinal cord
Create choroid plexuses
Choroid plexuses
Secrete cerebrospinal fluid
Microglia
CNS-specific immune cells
Are mobile and phagocytic in response to inflammation
Oligodendrocytes
Cells form myelin sheaths around axons, which insulates the axon.
2 types of Glial cells in the PNS
Schwann cells > form myelin sheaths (but only around one axon)
Satellite cells > surround neuron cell bodies in sensory adn autonomic ganglia. Provide nutrition to neuron cell bodies, protect neurons from heavy-metal poisons
Myelinated axons
Shwann cells or oligodendrocytes extensions repeatedly wrap around a segment o fan axon, forming tightly wrapped membranes rich in phospholipids
Like a hotdog (axon) in a tortilla (myelin)
Action potentials travel faster along myelinated axons than unmyelinated axons
Nodes of Ranvier
Gaps in myelin sheaths
When do myelin sheaths form
late in fetal development until the end of the first year after birth; then continues more slowly
What makes a nerve likely to regrow?
Close proximity between the two ends of an injured axon