Acute Cardiac (adults) Flashcards
Coronary artery disease (CAD)
- chronic stable angina
- acute coronary syndromes
- affects arteries that provide blood, oxygen, nutrients to myocardium
Ischemia
Insufficient oxygen supplied to meet requirements of tissue
Infarction
- necrosis (cell death) occurring after prolonged ischemia.
- decreased perfusion causes irreversible damage.
Atherosclerosis
- narrowing of lumen
- decreased perfusion
- mtissue ischemia/infarction
angina pectoris is…
chest pain
angina pectoris cause
temporary imbalance between coronary arteries’ ability to supply oxygen and myocardium’s oxygen demand ischemia is limited, no permanent damage
classic angina characteristics
- predictable (stress or exertion)
- relieved by rest/ntg
- limited in frequency, duration, intensity
- fixed atherosclerotic plaque
acute coronary syndrome is…
- unstable angina
- acute myocardial infarction
acute coronary syndrome results in…
atherosclerotic plague in coronary artery ruptures
- platelet aggregation
- thrombus formation
- vasoconstriction
% plaque = blocked blood flow
40
unstable angina characteristics
- progressive severity
- unrelated to activity
- unpredictable (stress/exertions)
- prinzmetal’s angina
unstable angina is…
- chest pain/discomfort occurring at rest or with exertion
- causes severe activity limitation
Prinzmetal’s angina
“variant” angina
- caused by coronary vasospasm
- usually associated with ST segment elevation
- no troponin or creatine kinase?
SEVEN DIMENSIONS (symptom eval)
- timing/onset
- location
- quality
- quantity
- aggravating
- alleviating
- associated
management goals for angina
- decrease workload of heart
- increase supply
- decrease demand
acute myocardial infarction
- prolonged supply/demand imbalance
- not relieved by rest, ntg
- ruptured plaque (embolism)
- coronary spasm
nstemi characteristics
- myocardial infarction “light”
- subendocardial (doesn’t go all the way through wall)
stemi characteristics
- transmural
cardiac biomarkers
- creatine kinase (ck)
- creatine kinase mb (ck-mb)
- troponin
increased CK but no MB =
not the heart, other catastrophic process
creatine kinase released by
brain
myocardium
skeletal muscles
creatine kinase-mb released by
myocardium band!
more specific to myocardium
troponin released by
myocardial specific
creatine kinase onset/peak/duration
2-6h/18h/72h
creatine kinase-mb onset/peak/duration
4-8h/24h/48-72h
troponin onset/peak/duration
3-12h/24-48h/5-14d