1 Opioid Meds

Question 0

Codeine

Answer 0

Acts directly on medullary cough center

Multiple schedules depending on mix

Question 1

Meperidine (Demerol)

Answer 1

Strong agonist 
UNIQUE QUALITIES: reduced smooth muscle spasm, prolonged/repetitive use + decreased renal clearance = normeperidine 
"Outdated"
Use < 48 hours
max 600 mg/24 hours

Question 2

Nalbupine (Nubain)

Answer 2

Agonist-antagonist
Kappa - agonist / mu - antagonist
Moderate to severe pain
Supra therapeutic doses = effect mimicking psychosis
Precipitates withdrawal symptoms in pt dependent on opioids
INCREASED CARDIAC WORKLOAD = ADR

Question 3

Naloxone (Narcan)

Answer 3

Antagonist
Hepatic metabolism
Oral administration INEFFECTIVE
Immediate withdrawal reaction when given to pts dependent on opioids