4.2.1 Pathophysiology of Diarrhea Flashcards
Patient has linear ulceration. What is the diagnosis?
Chron’s Dz
Answer
B) carcinoid (neuroendocrine tumor)
Describe how solute absorption/secretion is related to water absorption/secretion
What are some of the more important/common causes of acute diarrhea?
Drugs, Bacterial infection, Viral infection, Protozoa infection, Parasite infection, Traveler’s diarrhea
What are some of the pathophysiologies that cause diarrhea due to dismotility?
What is considered acute diarrhea? Chronic?
Acute: <2 wks
Chronic: >4 wks
What are some of the charcteristics features of bacterial entertoxins that cause diarrhea?
How does nutrient and electrolyte assimulation differ in regions of the adult intestine?
What are some labratory exams that could be useful in understanding the cause of a patient’s diarrhea?
CBC, electrolytes, BUN, Cr, total protein, albumin, globulin
Stool: weight, fat, culture, ova/parasite
Na, K, Mg, pH, occult blood, fecal WBC
laxative screen, C. diff PCR
Stool osmolality
Endoscopy
Abdominal imaging
What is considered fatty diarrhea?
> 14 g/day of fat is considered steatorrhea (normal is < 6 g/day)
Describe how permeability changes as you pass through the bowels
Decreases as you go through
What is the most common type of drug that causes acute diarrhea?
Antibiotics (duh, you’re changing the gut microflora)
What are the three characteristics of diarrhea?
>3 BM/day
Weight >200g/day
Increased liquidity
What is this condition?
Traveler’s diarrhea
Give some examples of pumps/channels/carriers present in intestinal cells