2.4.3 Pancreatitis Flashcards
What is the broad mechanism of pancreatitis?

Chronic pancreatitis is associated with what pain?
Left side pain that radiates to the back
Is chronic pancreatitis associated with high serum amylase and lipase?
NO
Why can acute pancreatitis be associated with hypoglycemia?
Islet of langerhan cells - will discharge insulin and lower blood glucose levels
What is different about the left side of this image vs the right?

Left side - fat cell without outlines - calcifications are blue
RIght side - normal
Microvascular leakage and endothelial injury will lead to what in pancreatitis?
Microvascular leakage - edema and ascities
Endothelial injury - thrombosis and DIC
What is pancreatitis?
Inflammation of the pancreas
How can pancreatitis relate to calcium levels?
Pancreatitis will be associated with hypocalcemia - due to calcium depositing in the necrotic pancreatic tissue
What sphincter allows for things to flow from the pancreas to duodenum?
Sphincter of oddi
What are some important characteristics to remember in chronic pancreatitis?

What is this an image of?

chronic pancreatitis
What are the white specks on this image?

White specks of calcium
What are some complications associated with acute pancreatitis?
Ascites containing enzymes
Paralytic ileus
DIC-ARDS-shock
Infection-pancreatic abscess
Psuedocyst of the pancreas
Chronic pancreatitis
Secondary diabetes
What is this an image of?

Acute pancreatitis
What are the important lab findings associated with pancreatitis?
Hypocalcemia is a sign of bad prognosis

Answer

A
A
C
C
A
B
What will cause the fat necrosis associated with pancreatitis?
Activation of lipolytic enzymes
What is this an image of?

Acute pancreatitis - associated hemorrhage
What is this an image of?

Acute pancreatitis - fat necrosis right side
Inflammed pancreas left side
What is the main culprit of chronic pancreatitis?
Alcohol
What are the basic lab findings associated with acute pancreatitis?
Elevated amylase and lipase
Possible hypocalcemia
How will a patient with acute pancreatitis present in clinic?
Sudden onset of epigastric pain, vomiting and abdominal distension
What is this an image of?

Necrotic surface
Pseudocyst
Activation of proteolytic enzymes will do what in pancreatits?
Act as chemotactic factors and cause inflammation