18.2 Protein Synthesis and Gene Expression Flashcards

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1
Q

What do proteins consist of?

A

Sequence molecules called Amino Acids

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2
Q

What determines the chemical properties of proteins?

A

The specific sequence of Amino Acids

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3
Q

What do the specific proteins synthesized by a cell determine?

A

The structure, function and development of the cell

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4
Q

What makes is the Genetic code?

A

The order of the base pairs in a DNA molecule

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5
Q

What does the genetic code determine for Amino Acids?

A

It determines how amino acids are strung together and how proteins are made

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6
Q

What is the Central Dogma of Gene expression?

A

The theory that genetic information flow from DNA to RNA to protein

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7
Q

What is Transcription?

A

When DNA is copied into an RNA molecule

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8
Q

Where does Transcription take place?

A

In the nucleus

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9
Q

What does Transcription require?

A

A special type of RNA molecule called RNA messenger (mRNA)

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10
Q

What does mRNA do?

A

Moves into the cytoplasm of the cell where the mRNA nucleotide sequence directs the synthesis of a polypeptide with the aid of another RNA molecule, Transfer RNA (tRNA)

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11
Q

What is the process of Translation?

A

When mRNA moves into the cytoplasm of the cell where the mRNA nucleotides sequence direct the synthesis of a polypeptide with the help of tRNA

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12
Q

What are Polypeptides?

A

Long chains of amino acids

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13
Q

What is a Codon?

A

In a gene, a set of 3 bases ex. ACC

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14
Q

What is the Genetic code always interpreted in?

A

The mRNA codon instead of the nucleotide sequence of the original DNA strand

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15
Q

What are the 3 important characteristics for the Genetic Code?

A
  • More than one codon can code for the same amino acid
  • It is continuous so it reads without spaces or punctuation
  • It is universal for all organisms
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16
Q

What happens in Transcription?

A

Information in a segment of DNA is copied into mRNA which carries it to the cytoplasm

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17
Q

How many strands of DNA are transcribed during Transcription?

A

Only one from each strand of DNA

18
Q

What is the Sense Strand?

A

The strand that is transcribed during transcription. The other is called the Anti-sense strand

19
Q

Which enzymes catalyse the synthesis of RNA?

A

RNA polymerases

20
Q

What is the Promoter Region?

A

A sequence of nucleotides on the DNA molecule that tell the RNA polymerase where to bind

21
Q

What happens once the RNA polymerase binds to the sense strand on DNA?

A

It opens a seperates a section of the double helix where it works its way along the DNA where it creates a section of mRNA that is complementary to the sense strand

22
Q

What is changed on the mRNA strand during translation?

A

Thymine is replaced with Uracil on the mRNA strand

23
Q

What signals RNA polymerases to stop producing mRNA?

A

A specific nucleotide sequence on the on the sense strand

24
Q

What needs to happen for proteins to be created?

A

The information on the mRNA strand must be translated into amino acid sequnces

25
Q

What works to translate the mRNA sequence when it reaches the cytoplasm?

A

A translator and protein synthesis equipment

26
Q

What does tRNA do?

A

Links each mRNA codon to its specific amino acid

27
Q

What tRNA made of?

A

A single strand that folds into a characteristic shape

28
Q

What is the Anti-codon?

A

A lobe of tRNA that contains three nucleotides that are complementary to the mRNA codon

29
Q

What is at the opposite end of tRNA?

A

The binding site for the Amino acid that corresponds to the codon

30
Q

What do ribosomes do?

A

They bring together mRNA strand and the tRNA molecules that carry the amino acids to build the polypeptides

31
Q

What is the third type of RNA found in ribosomes?

A

rRNA, which is a linear strand of RNA that remains associated with ribosomes

32
Q

When is Translation activated?

A

When an mRNA molecule binds to an active ribosome complex

33
Q

How does the mRNA bind to the ribosome complex?

A

In a way so that two adjacent codons are exposed

34
Q

What happens once the mRNA binds with the ribosome?

A

The tRNA molecule carrying an amino acid with the base pairs with the first exposed codon

35
Q

What happens once the first tRNA binds with the mRNA?

A

The second tRNA arrives at the next codon and binds. Enzymes then catalyze the formation of that joins the two amino acids. The the ribosome moves one codon down and the last tRNA molecule detaches leaving the amino acid

36
Q

What is Genomics?

A

The study of entire genomes, including interactions among multiple genes

37
Q

What is Proteomics?

A

The study of all the proteins that are produced by a given genome

38
Q

What is the function of mRNA?

A

Carries genetic info from DNA to protein synthesis equipment in the cytoplasm

39
Q

What is the function tRNA?

A

Carries a particular amino acid to the correct codon site in the protein synthesis equipment

40
Q

What is the function of rRNA?

A

Combines with a complex of proteins to form a ribsome