13.4 Flashcards

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1
Q

Where is the pancreas located and connected to?

A

Behind the stomach and is connected to the small intestine

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2
Q

What does the majority of the pancreatic tissue do?

A

Secretes digestive enzymes into the small intestine

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3
Q

Why is the pancreas considered an exocrine gland?

A

Because it secrets products through it ducts

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4
Q

What are Islets of Langerhans?

A

The endocrine cells of the Pancreas

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5
Q

What do the Islet cells of Langerhans secrete?

A

Insulin and Glucagon

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6
Q

Which cells secrete Insulin?

A

The beta cells of the pancreas

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7
Q

Which cells secrete Glucagon?

A

Alpha cells of the pancreas

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8
Q

What does insulin do?

A

Decreases the level of blood glucose

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9
Q

What does Glucagon do?

A

Increases the level of blood glucose

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10
Q

What are Insulin and Glucagon regulated by?

A

Negative feedback

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11
Q

How does insulin work?

A

It circulates throughout the body and acts on specific receptors to make the target cells more permeable to glucose

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12
Q

How does Glucagon work?

A

It stimulates the liver to convert glycogen back into glucose which is released into the blood

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13
Q

What is Diabetes Mellitus?

A

When the body doesn’t produce enough insulin, or doesn’t respond properly to insulin causing high blood sugar

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14
Q

What are the symptoms of Hyperglycemia from diabetes mellitus?

A

Fatigue

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15
Q

What will the body turn to without glucose from the blood?

A

Fat and Protein deposits which are less accessible and release ketones

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16
Q

What happens in the kidneys if there is very high blood sugar?

A

Kidneys cannot reabsorb all the sugar so it is excreted through urine which is also followed by water

17
Q

What can high blood sugar lead to?

A

Kidney failure, nerve damage, gangrene

18
Q

What is another name for type 1 diabetes?

A

Juvenile or insulin dependant

19
Q

What is another name for type 2 diabetes?

A

Adult onset or non-insulin diabetes

20
Q

What causes type 1 diabetes?

A

The immune system produces antibodies that attack and destroy the beta cells of the pancreas and as a result cannot produce insulin

21
Q

What causes type 2 diabetes?

A

The body’s cells stop responding to insulin and then the pancreas starts to produce less insulin over time

22
Q

How is type 1 diabetes treated?

A

Insulin

23
Q

How is type 2 diabetes treated?

A

Diet and exercise

24
Q

How are dogs used to treat diabetes?

A

Islet cells were isolated from does and then insulin cells were produced from those

25
Q

How is synthetic insulin produced now?

A

Through genetically engineered bacteria