Weight loss Flashcards
What drugs can cause weight gain?
What drugs can cause weight loss?
What OTC supplements can help with weight loss?
Antipsychotics, diabetes medications, Valproic acid, lithium, mirtazapine, steroids, hypothyroidism.
ADHD drugs, GLP-1 agonists, Pramlintide, SGLT2 inhibitors, Topiramate, Hyperthyroidism, Celiac disease, IBD.
Bitter orange, caffeine, guarana, green tea powder.
What drugs to avoid in weight loss conditions?
When should drugs be discontinued?
What to know about Phentermine/Topiramate MOA and side effects?
Pregnancy(all), Hypertension(Contrave, Qsymia caution), Depression(Contrave), Seizures(contrave, Qsymia caution), Taking opioids(contrave).
If 5% weight loss at 12 weeks doesn’t happen.
Sympathomimetic(stimulant), Release norepinephrine(phentermine), Topiramate(increases satiety and lowers appetite possibly by increased gaba, blocking glutamate receptors, inhibitor of carbonic anhydrase. REMS teratogenic risk. CI’d in pregnancy, Tachycardia. Qsymia is combo.
What to know about Naltrexone/Bupropion?
What to know about Lorcaserin(Belviq)?
What to know about Liraglutide?
Contrave. Lower food cravings(Naltrexone), Bupropion(lower appetite). CI’d in chronic opioid use, uncontrolled hypertension, seizure disorder, other bupropion-containing products, pregnancy, psychiatric disorders, Naltrexone blocks opioids.
Increase satiety as a 5-HT2C receptor agonist. Pregnancy CI’d, serotonin syndrome, hypoglycemia.
Saxenda, increase satiety, Victoza in diabetes. Risk of C-cell carcinomas, watch for in pregnancy, pancreatitis, hypoglycemia, nausea.
What to know about Lipase inhibitor?
What to know about phentermine?
What drug can treat gallstones?
Orlistat, Decrease absorption of dietary fats by 30%, PRegnancy, GI(flatus with discharge), fatty stool, Take ADEK and beta carotene at bedtime or separated by >2 hours, Max 30% of kcals from fat.
Sympathomimetics(stimulants), Adipex-P is brand name, cardiovascular disease(uncontrolled hypertension), hyperthyroidism, glaucoma, pregnancy, drug abuse. Tachycardia, increased agitation, increased BP, HR, BP, short-term up to 12 weeks.
Ursodiol.
