Sickle Cell Disease Flashcards
1
Q
What bugs are we worried about with sickle cell?
What vaccines are important in SCD?
What is non drug treatment of SCD?
A
Strep pneumo, Haemophilus, Neisseria.
Haemophilus B, PCV13 and Prevnar, Meningococcal conjugate series, pneumococcal pneumovax and pcv13 in any patient older than 6 if never received as part of a routine childhood series,.
Blood transfusions, the only cure is bone marrow transplantation, chelation therapy, Hgb should be no higher than 10 g/dL.
2
Q
What to know about hydroxyurea?
A
Stimulates production of HgbF. BW of myelosuppresion. Embryo-fetal toxicity, avoid live vaccinations, CBC with diff, ANC, contraception required, hazardous agent, Folic Acid. Wear sun protection.
