Sexual Dysfunction Flashcards
What natural drugs treat dysfunction?
What key drugs cause sexual dysfunction?
What to know about PDE-5 inhibitors?
Yohimbine, l-arginine, and panax ginseng.
Alcohol, Antidepressants, Antihypertensives, Antipsychotics, BPH medications.
Increases cGMP which permit blood flow in. Sildenafil(Viagara) start at 50 mg and take 1 hr before sexual activity, start at 25 mg in select conditions. Vardenafil start at 10 mg, Tadalafil(cialis) daily dosing is 2.5-5 mg daily, on demand is 5-20, start at 10 mg at least 30 min before activity.
What are the PDE-5 inhibitors side effects?
When to reduce starting dose?
When to take the pills?
Do not use with nitrates and riociguat. Color discrimination, hearing loss, vision loss, hypotension, priapism, immediate medical help if chest pain, headache, flushing, dizziness, dyspepsia, back pain (mostly with tadalafil).
> 65 years, using an alpha blocker, using a CYP 3A4 inhibitor, severe renal or liver disease.
15 minutes (avanafil), 30 minutes for tadalafil, 1 hour sildenafil and vardenafil.
What to know about Alprostadil?
What treated HSDD?
Prostaglandin E1 is a vasodilator, injection or pellet. Refrigerate, penile pain, priapism.
Agonist activity at 5-HT1A and antagonist activity at 5-Ht2A. Use in premenopausal women, Filbanserin (Addyi). CI’d with alcohol, REMS program required, in cobination with Cyp3A44 inhibitor, Hypotension, syncope.
