warfarin Flashcards
1
Q
M?
A
Inhibits hepatic production of vitK-dependent coagulation factors and cofactors
Inhibits VitK epoxide reductase, which reactivates vitK once oxidised so coagulation factors cannot be made.
2
Q
I?
A
prevents clot extension and recurrence in DVT or PE
prevents complications in AF/heart valve replacement
3
Q
C?
A
risk of haemorrhage, liver disease, trauma, pregnancy,ccp450 inhibitors/inducers, antibiotics
4
Q
A?
A
bleeding
epistaxis
retroperitoneal haemorrhage
