Anti-muscarinics-bronchodilators

Question 1

M

Answer 1

Bind to muscarinic receptor and act as competitive inhibitors of Ach. They reduce smooth muscle tone and reduce secretions from glands in the resp and GI tract. Also they cause relaxation of the pupillary constrictor muscle and ciliary muscles, causing dilatation and preventing accommodation respectively

Question 2

I

Answer 2

COPD-SAMA’s relieve breathlessness. LAMA’s prevent breathlessness and exacerbations
Asthma-SAMAs-relieve SOB in acute exacerbations with B2 agonists. LAMA’s are added to step 4.

Question 3

C

Answer 3

angle-closure glaucoma (increased IOP), arrhythmias

Question 4

A

Answer 4

dry mouth-not systemic so not absorbed as much