Antimotility/loperamide

Question 1

M

Answer 1

Opioid-agonist of opioid receptors in GI tract-increased non-propulsive contractions in the gut smooth muscle but reduced peristalsis-lower gut transit and increased anal sphincter tone. Increased time for water reabsorption and hardens stool

Question 2

I

Answer 2

Symptomatic treatment of diarrhoea-due to IBS or viral gastroenteritis

Question 3

C

Answer 3

acute UC, c.diff colitis, dysentery, E.coli

Question 4

A

Answer 4

GI effects-constipation, cramps, flatulence, toxicity if used with another opioid