Aminosalicylates

Question 1

M?

Answer 1

UC-release 5-ASA-anti-inflammatory and immunosuppresive effects specifically in gut
Delays delivery to gut
Sulf-sulfapyridine and 5-ASA-bacterial enzymes break this down and release it in the gut

Question 2

I?

Answer 2

Mesalazine-UC

Sulfasalazine-RA (DMARD)

Question 3

C?

Answer 3

aspirin hypersensitivity, PPI, lactulose

Question 4

A?

Answer 4

GI upset, headache, leucopenia, thrombocytopenia, renal impairment, oligospermia, serious hypersensitivity reaction