Digoxin Flashcards

1
Q

Mech of action?

A

Negatively chronotropic and positively inotropic
Decreases heart rate, increases contractility
Increases vagal tone
Less conduction at the AV node, slowing down ventricular rate.
In HF, it inhibits the Na/K ATP ase so sodium accumulates inside cells, so Ca does too-more contractile force

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2
Q

I?

A

AF, atrial flutter to reduce ventricular rate

severe HF-third line or earlier of existing AF

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3
Q

C?

A

arrhythmias, renal failure, hypokalaemia, hypomagnesia, hypercalcaemia, loop and thiazides, amiodarone, CCB spironolactone and guinine

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4
Q

A?

A

bradycardia, GI, rash, dizziness, visual disturbances, arrhythmias, digoxin toxicity

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