Vancomycin

Question 1

M

Answer 1

Inhibits growth and cross-linking of teh peptidoglycan chains and so inhibiting synthesis of the cell wall of G+ bacteria/anaerobic bacteria.

Question 2

I

Answer 2

Treatment of Gram-positive infections eg endocarditis when severe
Treat AB-associated colitis caused by C.diff as a second line to metronidazole

Question 3

C

Answer 3

renal impairment, elderly, aminoglycosides, loop diuretics, ciclosporin

Question 4

A

Answer 4

thrombophlebitis at infusion site, red man syndrome, hypersensitivity, nephrotoxicity, ototoxicity, blood disorders