Anti-histamines-(old)

Question 1

M?

Answer 1

Mech of Action
• Antagonist of H1 receptors-prevents H1-receptor mediated hypersensitivity and effects of histamine (wheal , flares, erythema, itching, sneezing, conjunctivitis, urticaria, oedema and hypotension.

Question 2

I?

Answer 2

Indications
• First line treatment for allergies and hayfever
• To relieve pruritus and urticaria due to insect bites, infections and drug allergies
• As adjunctive treatment in anaphylaxis after adrenaline
• N and V

Question 3

C?

Answer 3

Contraindications

• Sedating, so avoided in severe liver disease

Question 4

A?

Answer 4

Adverse Effects

• Sedating