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Microbiology -Medical-Prof > Virology > Flashcards

Virology Flashcards

1
Q

Protein coat of virus is called ?/

593

A

Capsid

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2
Q

Subunits of capsid is called ??

A

Capsomers

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3
Q

Viral nucelic acids is called ??

A

DNA / RNA

Not both

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4
Q

Basic structure of virus - Content ??

A
  1. Viral nucleic acids
  2. Capsid
  3. Envelope

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4
Q

Function of envelope ??

A
  1. Protection
  2. Attachment to the target cell

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5
Q

All virus are - H/D ??

A

Haploid

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6
Q

Envelope content of a virus ??

A

Surface glycoprotein

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7
Q

Capsid made of — ??

A

Protein

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8
Q

Function of capsid ??

A
  1. Protection
  2. Attachment
  3. Act as antigen
  4. Provide structural symmetry of virus

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9
Q

Cuase of geometry symmetry of virus ??

A

Arrangement of capsomere

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10
Q

Geometry symmetry of virus type ??

A
  1. Icosahedral
  2. Helical
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11
Q

Icosahedral virus ??

A

20 triangle - symmetric figure

594

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12
Q

Helical capsomere of virus ??

A

Hollow coil - Rod shaped

envelope present

594

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13
Q

Virion definiton ??

A

Complete virus particle that is structurally intact & infectious `

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14
Q

Polio virion example ??

A

NA covered by protein coat

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15
Q

Herpes virion part ??

594

A

Whole virus – Virion

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16
Q

Pseudovirus definition ??

A

PV contain host cell DNA instead of viral DNA within the capsid

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17
Q

Why non-enveloped viruses are resistant to detergent ??

A

The presence of an envelope confers instability on the virus

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18
Q

Examples of atypical virus like Agents ??

A
  1. Defective
  2. Pseudovirus
  3. Viriods
  4. Prions

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19
Q

Defective virus definition ??

A

A virus that composed of viral nucleic acid & proteins but cannot replicate without a helper Virus

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19
Q

Example of defective virus ??

A

Hepatitis-D

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19
Q

icosahedral example ?

A

HBV
Herpes simplx
adenovirus
rubella

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20
Q

helical virus example ?

A

IMR
influenza
measles
rabies

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20
Q

Feco-oral ?

A

HAV
rota
polio

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21
Q

insect virus <

A

yellow fever

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22
Q

Viriods disease ??

A

Plant d
Not implicated Human diseases

595

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23
Q

Infection induces AB & Inflammation P/A in prions ??

A

NOOOOOOOO
in prions

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23
Q

Does prions have NA ??

A

NOOOOOOOOOOOOO

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23
Q

Defcetive virus cause ??

A

Mutation / deletion of part of their genetic amterials

595

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23
Q

Viriods NA ??

23
Q

Protein coat & Envelope present where ??

A

Virus
Not in viriods

595

23
Q

Virus NA ?

A

DNA / RNA

595

24
Q

Prions appearance in Electron microscope ???

A

Filamentous rods
Amyloid like

596

25
Q

envelope thaka valo na kharap ?

A

kharap
confers instability
sensitive to heat drying detergents and lipid solvents such as alchohol and ether

26
Q

smallest virus <

27
Q

largest virus?

28
Q

HDV need which part of HBV for replication ?

A

surface Atg

29
Q

enveloped virus name ?

30
Q

SS virus <

31
Q

segmented virus ?

A

Influenza
rota
retro
arena
bunya

31
Q

DS virus name <

32
Q

vertical meaning <

A

mother to child

33
Q

horizontal meaning >

A

person to person

34
Q

mosquito bite disease <

A

DYE-C
dengue
yellow fever
encephalitis
chikungunya

35
Q

Transplacental perinatal infections by which virus ?

A

CPR-
HIV- HBV HCV

Cytomegalovirus
ParvoB19
Rubella

36
Q

which bacteria transplacentally /

A

treponema pallidum
listeria

36
Q

breast feeding ?

A

HIV
Human T cell lymphotrophic virus -HTLV
CMV

37
Q

at the time of birth which virus ?

A

HIV- HBV HCV

herpes-2
papilloma

38
Q

which protozoa transplacentally /

A

toxoplasma gondii

38
Q

Rabies cell tropism >

39
Q

Herpes cell tropisim <

A

heparan sulfate

fibroblast growth factor

39
Q

which bacteria at the time of birth <.

A

neisseria
chlamydia
group-B streptococcus

40
Q

measles and HIV cell tropism <

A

HIV = CD4+

M= CD46

41
Q

live vaccine name ,

A

MM RR VZ
measles
mumps
rubella
rota
varicella
zooster

42
Q

killed vaccine name <

43
Q

intracytoplasmic inclusion ?

A

negri -rabies
guarnieri - small pox + vaccinia

44
Q

intanuclear inclusion ?

A

cow dry type-A — herpes simplex + zooster
cow dry type -B—- poliomyelitis

45
Q

both intranucler + cytoplasmic >

46
Q

LIVE + KILLED ?>?

A

polio
I-A + B

47
Q

Virus causing diarrhea <

A

norwalk
calici
rota
adeno
astro
corona

48
Q

CPE - Cytoplasm <

A

inclusion bodies
vacuoles

48
Q

CPE change in nucleus <

A

inlusion bodies
thickening of N
swelling
nucleolar changes
margination of chromatin

611

49
Q

slow virus infection name >
612

A

kuru
creutzfeldt -jakob

50
Q

CPE - membrane <

A

loss of adherence
cell fusion - syncytia

51
Q

CPE-CELLULAR ,

A

lysis
disintregation

51
Q

;atent site of EPstein barr ?

A

B lymphocyte

51
Q

mRNA vaccine of corona ?

A

moderna
\
pFize/ Biontech

52
Q

latent infection site of Varicella -Z ?

A

TRIGEMINAL / thoracic ganglia

52
Q

chronic carrier infection ?

A

HCV
HBV
CMV
neonatal rubella

53
Q

latwnt site to Herpes - 1 >

A

cranial sensory ganglia

54
Q

Protein subunit vaccine of Corona ?

55
Q

latent site of Herpes-2 /

A

lumbar and sacral sensory ganglia

56
Q

vector vaccine of covid <

A

JOHNSON & JOHNSON
oxford/astrazenica

56
Q

5th disease name >

A

erythema infectiosum
slapped check syndrome
Parvo-B19

Microbiology -Medical-Prof (49 decks)

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