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Microbiology -Medical-Prof > Dengue+Chikungunya > Flashcards

Dengue+Chikungunya Flashcards

1
Q

symptomatic dengue clinical manifestation ?

A

classical dengue fever
D hemorrhagic fever
D shock sy ndrome

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2
Q

clinical features of classical dengue ?

A

pain in muscles & joints
breakbone pain
maculopapular rash
leukopenia
fever - malaise - cough - headache
myalgia - arthalgia
retro-orbital pain

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3
Q

agent of dengue ?

A

female aedes aegypti

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4
Q

aegypti VS albopticus ?

A

A e = Nervous fider

al = Aggressive fider

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5
Q

aegypti bite & meal no ?

A

> 1 bite to complete meal
1 meal to complete gonotropic cycle

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6
Q

viremia high in which Virus disease ?

A

dengue
yellow fever

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7
Q

serotypes of dengue ?

A

DEN
1 2 3 4

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8
Q

most dangerous serotype of dengue ?

A

2

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9
Q

DEN 5 country & year ?

A

2015
bangkok

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10
Q

type of virus ?

A

RNA
enveloped

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11
Q

familly of dengue ?

A

flaviviridae
ARBO virus

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12
Q

what is ARBO virus ?

A

virus trasnmit from arthropod
600 virus

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13
Q

biological control of dengue ?

A

Bacillus thuriengiensis israelensis
Bti

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14
Q

tiger mosquito which one ?

A

aedes albopticus

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15
Q

DHF characteristics?

A

classical findings
+ shock
+ hemorrhage in GI tract & skin

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16
Q

lab Dx of DHF ?

A

Thrombocytopenia
hypoproteinemia
inc BT
inc PT

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17
Q

Pathogenesis of dengue fever / DSS / ESS ?

A

698

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18
Q

Vaccine name of dengue ?

A

dengavaxia
Qdenga

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19
Q

dengavaxia dose ?

A

3 dose
0.5 ml —- SC — 6 MONTH intervel

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20
Q

BD status of dengue vaccine ?

A

not approved

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21
Q

CBC report of Dengue ?

A

thrombocytopenia
Hematocrit = inc &raquo_space;20%
prothrombin time = inc

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22
Q

why hematocrit inc in dengue ?

A

plasma leakage
platelet = dec
vascular endothelial destruction

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23
Q

DSS fatality rate ?

A

10%

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24
Q

fever + rash in which viral disease ?

A

chicken pox / varicella
measles
rubella
HIV-1

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25
7th day which test ?
AB test
26
what is NS1 ?
non-structural protein
27
(1-5) day - which test ?
NS1
28
Atg test reason ?
for Diagnosis
29
AB test reason ?
for prognosis
30
why after 1 week NS1 (-) ??
NS1 level declines as the immune respond builds and AB begins to neutrilize the virus
31
is there any specific Tx ?
no symptomatic Tx
32
evidence of plasma leakage?
hematocrit >>20% Vascular permeability +++ plasma leakage in DHF == lost for (24-48) hour
33
DHF stage ?
febrile critical convalesent
34
what is EDS ?
involvement of liver kidney brain/heart con-infection co-morbidity if seen in DHF , than it is the result of prolonged shock leading to organ failure 700
35
mosquito borne viral disease ?
yellow f dengue chikungunya zika west nile japanese encephalitis
36
can you given aspirin in the pt ?
NO bleeding risk
37
can you give NSAID >
NO bleeding risk GI bleeding masking syndrome
38
how to identify dengue IgG / IgM ?
ELISA Rapid ICT
39
D in 🤰 ??
fetal death LBW premature birth
40
disease by aegypti ?
dengue C Zika yellow f
41
Zika child manifestation ?
Encephalopathy
42
how to confrim Dengue Dx >
rtPCR
43
Which kit used in dengue ? Interpretaion
rapid ICT + within (15-20) minutes
44
function of non-structural protein ?
replication
45
function of structural protein ??
structure formation
46
danger signs of dengue?
Ab pain - intense & sustained persistant vomiting restlessness/somnolence hypothermia abrupt change of fever
46
importance of capillary refil time ?
to assess hypovolemia
47
dengue vs C ?
D - Myalgia + H + S + Thrombocytopenia + leukopenia C - Arthalgia + fever + rash + lymphopenia
48
time of biting of dengue mosquito >
now any time as change in characteristics
49
sylhet condition of dengue ?
less
50
dead end host of dengue >
human
51
which one reduce transmission of dengue ?
wolbachia
51
platelet count in dengue ??
< 100000 /mm3
52
1st (2-3) rd day dengue rash status ?
diffuse flashing fleeting eruption over face neck chest
53
3rd-4th day dengue rash status ?
maculopapular rash rubelli rash
54
dnegue vaccine type ?
live attenuated
55
Maculopapular rash + encephalitis ????
D C Measles
56
Maculopaular rash = ??
D C Measles rubella CMV infectious mononucleosis HIV syphillis typhoid & para T
57
chancre / ulcerating nodules ?/
syphilis anthrax typhus - tick & mite trypno-somiasis
58
joint pain type ??
emon vabe chole jeno betha kom hoy 703

Microbiology -Medical-Prof (49 decks)

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