Dengue+Chikungunya Flashcards
symptomatic dengue clinical manifestation ?
classical dengue fever
D hemorrhagic fever
D shock sy ndrome
clinical features of classical dengue ?
pain in muscles & joints
breakbone pain
maculopapular rash
leukopenia
fever - malaise - cough - headache
myalgia - arthalgia
retro-orbital pain
agent of dengue ?
female aedes aegypti
aegypti VS albopticus ?
A e = Nervous fider
al = Aggressive fider
aegypti bite & meal no ?
> 1 bite to complete meal
1 meal to complete gonotropic cycle
viremia high in which Virus disease ?
dengue
yellow fever
serotypes of dengue ?
DEN
1 2 3 4
most dangerous serotype of dengue ?
2
DEN 5 country & year ?
2015
bangkok
type of virus ?
RNA
enveloped
familly of dengue ?
flaviviridae
ARBO virus
what is ARBO virus ?
virus trasnmit from arthropod
600 virus
biological control of dengue ?
Bacillus thuriengiensis israelensis
Bti
tiger mosquito which one ?
aedes albopticus
DHF characteristics?
classical findings
+ shock
+ hemorrhage in GI tract & skin
lab Dx of DHF ?
Thrombocytopenia
hypoproteinemia
inc BT
inc PT
Pathogenesis of dengue fever / DSS / ESS ?
698
Vaccine name of dengue ?
dengavaxia
Qdenga
dengavaxia dose ?
3 dose
0.5 ml —- SC — 6 MONTH intervel
BD status of dengue vaccine ?
not approved
CBC report of Dengue ?
thrombocytopenia
Hematocrit = inc »_space;20%
prothrombin time = inc
why hematocrit inc in dengue ?
plasma leakage
platelet = dec
vascular endothelial destruction
DSS fatality rate ?
10%
fever + rash in which viral disease ?
chicken pox / varicella
measles
rubella
HIV-1
7th day which test ?
AB test
what is NS1 ?
non-structural protein
(1-5) day - which test ?
NS1
Atg test reason ?
for Diagnosis
AB test reason ?
for prognosis
why after 1 week NS1 (-) ??
NS1 level declines as the immune respond builds and AB begins to neutrilize the virus
is there any specific Tx ?
no
symptomatic Tx
evidence of plasma leakage?
hematocrit»_space;20%
Vascular permeability +++
plasma leakage in DHF == lost for (24-48) hour
DHF stage ?
febrile
critical
convalesent
what is EDS ?
involvement of liver kidney brain/heart
con-infection
co-morbidity
if seen in DHF , than it is the result of prolonged shock leading to organ failure 700
mosquito borne viral disease ?
yellow f
dengue
chikungunya
zika
west nile
japanese encephalitis
can you given aspirin in the pt ?
NO
bleeding risk
can you give NSAID >
NO
bleeding risk
GI bleeding
masking syndrome
how to identify dengue IgG / IgM ?
ELISA
Rapid ICT
D in 🤰 ??
fetal death
LBW
premature birth
disease by aegypti ?
dengue
C
Zika
yellow f
Zika child manifestation ?
Encephalopathy
how to confrim Dengue Dx >
rtPCR
Which kit used in dengue ? Interpretaion
rapid ICT +
within (15-20) minutes
function of non-structural protein ?
replication
function of structural protein ??
structure formation
danger signs of dengue?
Ab pain - intense & sustained
persistant vomiting
restlessness/somnolence
hypothermia
abrupt change of fever
importance of capillary refil time ?
to assess hypovolemia
dengue vs C ?
D - Myalgia + H + S + Thrombocytopenia + leukopenia
C - Arthalgia + fever + rash + lymphopenia
time of biting of dengue mosquito >
now any time
as change in characteristics
sylhet condition of dengue ?
less
dead end host of dengue >
human
which one reduce transmission of dengue ?
wolbachia
platelet count in dengue ??
< 100000 /mm3
1st (2-3) rd day dengue rash status ?
diffuse flashing
fleeting eruption over face neck chest
3rd-4th day dengue rash status ?
maculopapular rash
rubelli rash
dnegue vaccine type ?
live
attenuated
Maculopapular rash + encephalitis ????
D
C
Measles
Maculopaular rash = ??
D
C
Measles
rubella
CMV
infectious mononucleosis
HIV
syphillis
typhoid & para T
chancre / ulcerating nodules ?/
syphilis
anthrax
typhus - tick & mite
trypno-somiasis
joint pain type ??
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