Rabies Flashcards
shape of rabies virus ?
bullet/rod
pox virus shape /
box/brick
rota virus shape /
sphere
is there any envelope in rabies >?
YES
type of virus ?
RNA-Rhabdovirus
disease caused by R ?
Encephalitis
Which system is involved ?
CNS
Rbies day /
28 sep
RNA type of rabies ?
Negative polarity
Mortality of rabies ?
100%
prevention of rabies ?
100%
100% mortality disease ?
rabies
Tetanus
mode of transmission of rabies ?
1.bite of rabid animal
2.aerosols of bat secretions containing rabies virus
3.transplant of cornea
653
pathogenesis of rabies ?
654
what is negri body ?
eosinophilic cytoplasmic inclusion body
encephalitis characteristics?
death of neurons
demyelination
rabies tranport to CNS how ?
retrograde axonal transport to CNS
Postmortem Dx of rabies ?
Negri body
CPE of rabies ?
negri body
reservoirs of rabies ?
dogs-99%
cat
hyena
fox
wolf
vampire bat
negri body is seen by which stain ??
H & E
Incubation period and distance relation >??
D +++++++++++
IP +++++++++++++++
How to identify rabid animal /
mukh theke lala
jhimabe
why hydrophobia ?
H2O - Respiratory muscle spasm - spasm of thraot muscles
655
fear when feeling a breeze ?
aerophobia
types of rabid vaccine ?
HDCV
rabies vaccine absorbed -RVA
purified chick embryo cell vaccine - PCECV
nerve tissue vaccine - NTV
Duck embryo vaccine DEV
live attenuated vaccine
disease when post-exposure vaccination ?
R
T
diptheria
wound management ?
656
why suture contraindicated ?
bite wound open thake
deeper tissue te spread korte pare
why soap and running water ?
to kill envelope
passive immunization process ??
RIG
RIG types ?
Rabies Immuno gLobulin human - HRIG
Antirabies serum - equine
equine dose ?
40IU per kg body weight
RIGH dose ?
20IU/kg/body weight
BD te which vaccine
HDCV
HDCV by which company ?
incepta
500 taka
why Vacccine and RIG in different site ?
jeno vaccine er active ATg
RIG er AB ke neutriliza na kore
ideal vaccine site ?
deltoid
active passive immunity in which disease ?
R + T
Who are given pre-exposure prophylaxis ?
veterinarians
zookeepers
travelers of areas of hyperendemic areas
dose of pre-exposure prophylaxis ?
0-7-21/28
Though motality 100% tao keno pre-exposure nai ??
rabid dog e to sobai exposed na
long exposure period
budget issue
time to get achieve active immunity ??
2-16 weeks
vaccien type of R ?
killed
any contraindication ??
NO
Vaccine kader deya jabe ?
sobaike - na dile 100% - mortality
incubation period of R ?
2-16 week
vaccine given criteria ?
to complete full dose
early incubation period e dite hobe - within 7 days
stage of acute neurological phase ?
encephalic - furious 80%
paralytic - dumb 20%
neurotropic virus name ?
Polio
rabies
mumps
measles
herpes simplex
echo
coxsackie
BD vaccine name ?
rabi-vax
post-exposure dose ?
0.5ml
0-3-7-14-28 `
how to immunize dog ??
at 3-4 month of age
whole vaccine regimen ?
652
negri body site ?
purkinje cells of cerebellum
pyramidal cells of hippocampus
cortical and brainstem neurons
kono kukur kamor dile kukur ke ki korba >?
observe 10 day
tar S/S dekhbo
s/s = YES = brain biopsy
sis=NO = vaccine
re-exposre vaccine ?
same IV + IM
just IV = 0.1ml
age vaccine diye thakle
re-exposure hole ki korba ?
<3month kamor dile = no vaccine
»> 3 month = post exposure prophylxis
vaccine er kotodin por AB toiri hoy ?
2-3 week
ei time risk na nite ki dei <
RIG
Sob vaccine age age dei0 tao eta dei na keno ??
long incubation period
age vaccine diye lav nai
amra to jani na kokhon exposure hobe
bangla of rabies <
jolatonko
why name Jolatonko <
spasm of thraot mucles
painful laryngeal spasm