Hepatitis B Virus Flashcards

1
Q

Family of HBV ?

A

Hepadnavirus

671

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2
Q

Envelop of HBV ?

A
  1. HBsAg
  2. Lipid

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3
Q

Outstanding characteristics of HBV ??

A
  1. Acute & chronic hepatitis
  2. Hepatocellular carcinoma
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4
Q

Antigens of HBV ??

A
  1. HBsAg
  2. HBcAg
  3. HBeAg

s-c-e

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5
Q

Surface antigen of HBV ??

A

HBsAg

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6
Q

HBsAg importance ???

A

Lab diagnosis & immunization

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7
Q

Core antigen of HBV ??

A

HBcAg

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8
Q

The antigen that secreted from infected cell is called ??

A

HBeAg

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9
Q

Core antigen function In HBV ??

A

Forms the nucleocapsid core of the virion

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9
Q

HBeAg indicator of —??

A

Infectivity/ Transmissibility

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10
Q

Horizontal transmission of HBV ??

A
  1. Transfusion of infected unscreened blood products
  2. Sexual intercourse
  3. Injection drugs
  4. Tattos
  5. Close living quaters

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11
Q

Outcome of subclinical infection by HBV >??

A

Recovery

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11
Q

Vertical transmission of HBV ??

A
  1. HBsAg (+) Mother
  2. Delivery birth canal
  3. Post natal-Breast feeding \Prenatal - Placenta

672

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12
Q

Complications of HBV ??

A
  1. Fulminant live failure
  2. Chronic liver hepatitis
  3. Cirrhosis of liver
  4. Hepatocellular Ca

672

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13
Q

Acute hepatitis outcome ??

A

=Recovery
=Fulminant liver failure

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14
Q

Chronic carrier of HBV outcome ??

A
  1. Cirrhosis of liver
  2. Hepatocellular Ca

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15
Q

Antigens of HBV in the serum ??

A
  1. HBsAg
  2. HBeAg

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15
Q

Acute liver failure HBsAg state ??

A

-
negative

673

16
Q

Active ionfection indicator which antigen ??

16
Q

Antobodies of HBV in the serum ??

A
  1. Anti HBc IgM
  2. Anti HBs IgG
  3. Anti HBe IgM

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17
Q

In highly infectious patient which antigen in serum ??

18
Q

Anti HBs IgG IN blood indicated ??

A
  1. Previous infection
  2. Previous vaccination

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19
Q

Surest marker of Active infection ??

A

Anti HBc IgM

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20
Q

Detection of Anti HBe IgM is —-??

A
  1. Recovery
  2. Low transmissibility

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21
Strong evidence of infectious virions is present is --------??
Viral DNA | 674
22
Previous infection discovered by Anti HBsAg IgG ??
(+) Anti HBc ` | 673
23
Previous vaccination discovered by Anti HBsAg IgG ??
(-) Anti HBc
23
Window period in HBV infection ??
Time between the disappearance of a specific antigen & the appearance of antibody against that particular antigen | 675
24
Which seromarker is positive during window period ??
Anti-HBc IgM Ab | 675
25
The most important & readily detectable seromarker ???
HBsAg | 675
26
If I found HBsAg (-) is it free from HBV ??
NOOOOO maybe patient in window period | 675
27
Importance of window period in HIV ??
Diagnosis become difficult | 675
28
What is the next procedure ??
Check the Anti HBc IgM | 675
28
HBsAg in undetectable level when ??
3-6 month after infection | 676
29
Tx of HBV ??
Pegylated alpha interferon | 676
30
First detected Ab in HBV ??
Anti HBc IgM | 676
31
Names of hepatotrophic viruses ??
1. HAV 2. HBV 3. HCV 4. HDV 5. HEV | 666
32
HGV virus name <>
GB virus C / human hepe-gi-virus / pegivirus H 349