Hepatitis B Virus

Question 1

Family of HBV ?

Answer 1

Hepadnavirus

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Question 2

Envelop of HBV ?

Answer 2

1. HBsAg
2. Lipid

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Question 3

Outstanding characteristics of HBV ??

Answer 3

1. Acute & chronic hepatitis
2. Hepatocellular carcinoma

Question 4

Antigens of HBV ??

Answer 4

1. HBsAg
2. HBcAg
3. HBeAg

s-c-e

Question 5

Surface antigen of HBV ??

Answer 5

HBsAg

Question 6

HBsAg importance ???

Answer 6

Lab diagnosis & immunization

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Question 7

Core antigen of HBV ??

Answer 7

HBcAg

Question 8

The antigen that secreted from infected cell is called ??

Answer 8

HBeAg

Question 9

Core antigen function In HBV ??

Answer 9

Forms the nucleocapsid core of the virion

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Question 9

HBeAg indicator of —??

Answer 9

Infectivity/ Transmissibility

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Question 10

Horizontal transmission of HBV ??

Answer 10

1. Transfusion of infected unscreened blood products
2. Sexual intercourse
3. Injection drugs
4. Tattos
5. Close living quaters

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Question 11

Outcome of subclinical infection by HBV >??

Answer 11

Recovery

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Question 11

Vertical transmission of HBV ??

Answer 11

1. HBsAg (+) Mother
2. Delivery birth canal
3. Post natal-Breast feeding \Prenatal - Placenta

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Question 12

Complications of HBV ??

Answer 12

1. Fulminant live failure
2. Chronic liver hepatitis
3. Cirrhosis of liver
4. Hepatocellular Ca

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Question 13

Acute hepatitis outcome ??

Answer 13

=Recovery
=Fulminant liver failure

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Question 14

Chronic carrier of HBV outcome ??

Answer 14

1. Cirrhosis of liver
2. Hepatocellular Ca

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Question 15

Antigens of HBV in the serum ??

Answer 15

1. HBsAg
2. HBeAg

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Question 15

Acute liver failure HBsAg state ??

Answer 15

-
negative

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Question 16

Active ionfection indicator which antigen ??

Answer 16

HBsAg

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Question 16

Antobodies of HBV in the serum ??

Answer 16

1. Anti HBc IgM
2. Anti HBs IgG
3. Anti HBe IgM

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Question 17

In highly infectious patient which antigen in serum ??

Answer 17

HBeAg

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Question 18

Anti HBs IgG IN blood indicated ??

Answer 18

1. Previous infection
2. Previous vaccination

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Question 19

Surest marker of Active infection ??

Answer 19

Anti HBc IgM

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Question 20

Detection of Anti HBe IgM is —-??

Answer 20

1. Recovery
2. Low transmissibility

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Question 21

Strong evidence of infectious virions is present is ——–??

Answer 21

Viral DNA

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Question 22

Previous infection discovered by Anti HBsAg IgG ??

Answer 22

(+) Anti HBc `

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Question 23

Previous vaccination discovered by Anti HBsAg IgG ??

Answer 23

(-) Anti HBc

Question 23

Window period in HBV infection ??

Answer 23

Time between the disappearance of a specific antigen & the appearance of antibody against that particular antigen

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Question 24

Which seromarker is positive during window period ??

Answer 24

Anti-HBc IgM Ab

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Question 25

The most important & readily detectable seromarker ???

Answer 25

HBsAg

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Question 26

If I found HBsAg (-)
is it free from HBV ??

Answer 26

NOOOOO
maybe patient in window period

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Question 27

Importance of window period in HIV ??

Answer 27

Diagnosis become difficult

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Question 28

What is the next procedure ??

Answer 28

Check the Anti HBc IgM

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Question 28

HBsAg in undetectable level when ??

Answer 28

3-6 month after infection

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Question 29

Tx of HBV ??

Answer 29

Pegylated alpha interferon

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Question 30

First detected Ab in HBV ??

Answer 30

Anti HBc IgM

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Question 31

Names of hepatotrophic viruses ??

Answer 31

1. HAV
2. HBV
3. HCV
4. HDV
5. HEV

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