Helicobacter Pylori Flashcards

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1
Q

(+) result (Biochemical) of H.Pylori ??

A
  1. Oxidase
  2. Urease
  3. Catalase

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2
Q

Important properties of H pylori ??

A
  1. Gram (-)
  2. Multiple flagella = Motile
  3. Microaerophilic

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3
Q

What is microaerophilic ??

A

Requires less O2 CONC for survival

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4
Q

Rapid Dx procedure to identify infectious H pylori >??

A

Urea breath test

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4
Q

Disease caused by H pylori ??

A
  1. PUD
  2. Gastritis
  3. Gastric Carcinoma
  4. Mucosal associated lymphoid tissue MALT lymphomas

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5
Q

Specimen collection ??

A
  1. Gastric biopsy specimens
  2. Blood

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6
Q

Blood importance of H pylori specimen ??

A

Determination of serum AB

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7
Q

Non invasive test ??

A
  1. Urea breath test
  2. detection og IgG AB in serum
  3. 13C bicarbonate assay
  4. PCR-stool dental plaque water

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7
Q

Invasive test for H Pylori ??

A
  1. Gram staining
  2. Giemsa staining
  3. PCR
  4. Rapid urease test -RUT
  5. Biopsy-Endoscopy

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8
Q

PUD tx ??

A

Triple therapy

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8
Q

Triple Therapy ??

A
  1. PPI
  2. Amoxicillin
  3. Clarithromycin
  4. Metronidazole
  5. 7 days

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9
Q

Media for H P ?

A

Skirrow media at 42deg C

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10
Q

Urea breath test procedure ??

A
  1. Swallow urea labled with isotope
  2. If organism present urease will cleave the ingested urea
  3. Radiolabeled CO2 is evolved
  4. Radioactivity in breath

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