Corynebacterium Flashcards

1
Q

pathogenic corynebacterium name ??

A

C diptheriae
C renale
C pseudotuberculosis
C ulcerans
C haemolyticum

191

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2
Q

Non-pathogenic corynebacterium name ??

A

C acnes
C xerosis
C hoffmani
C pseuogenitalium

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3
Q

Types of corynebacterium ??

A
  1. gravis
    mitis
    intermediate
    belfanti

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4
Q

Morphology of C d ??

A
  • G + rod
  • club shaped
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5
Q

shape of C d ??

A

pairly - V + L
in group - chinese letters

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6
Q

NON - character of C d ??

A

NON- spore + motile

191

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7
Q

Granules type of C d ?

A

metachromatic granules

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8
Q

culture media of C d ??

A

blood agar
\
blood tellurite agar
/
Loefflers serum slop media

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9
Q

characteristics of metachromatic granules ??

A

dye stain korle
cell - blue
grabules - red

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10
Q

why slop in media ??

A

to inc the surface area
easy access to collect specimen
easy observation

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11
Q

disease caused by C d»

A

respiratory / cutaneous Diptheria

192

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12
Q

pathogenecity of C d&raquo_space;>

A

192 + 190

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13
Q

which C d produced Diptheria toxin ??

A

lysogenic strains of C d

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14
Q

clinical features of C d ??

A
  • Pharyngitis
    tonsilitis
    sore throat
    pseudomembrane
    cervical adenitis + edema
    Bull neck apperan
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15
Q

wHAT is bull neck appearance??

A

pseudomembranous pharyngitis + lymphadenopathy

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16
Q

2nd week complications of C d ??

A

Myocarditis

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17
Q

1st week complications of C d ??

A

extension of Pseduomembrane to the Larynx & trachea - Airway obstruction

193

18
Q

3rd week complications of CD ??

A

Nerve weakness / paralysis
pralaysis - muscles of soft palate + pharynx - regurgitation of fluids in nose

19
Q

enriched media of C d ?/

A

blood agar
chocolate agar
Loefflers serum slop media

20
Q

Microscopic examination
Gram stainiung result ??

A

G + bacilli
chinese letter apperance

21
Q

Albert stainign result of C d ??

A

Bacilli - blusih green
metachromatic granules - brick red

22
Q

selective media for C d?/

A

K tellurite agar media
Tinsdale media - black colony

194

22
Q

acute sore throat causing bacteria ??

A

C d - acute emergency
/
Streptococcus pyogens - long term

23
Q

in-VIV0 toxigenicity test ?/

A

Animal inoculation test

194

23
Q

in-VITRO toxigenicity test ??

A

PCR
\
ELISA
/
Eleks gel dissuision precipitin test
/
Immunochromographic

24
Q

elecks test procedure ??

25
Q

D vaccine name ??

A

D toxoid

197

26
Q

How given ??

A

Pentavalent vaccine

27
Q

Dose of vaccine ??

A

3 dose
6-10-14 weeks of age

28
Q

who are called Diptheroids ?

A

Non-pathogenic species of C

198

29
Q

Why chinese letter by C d ??`

A

due to incomplete seperation

30
Q

sore throat cAUSING fungi ?/

31
Q

M/A of diptheria toxin ??

32
Q

which stain demonstrate metachromatic granules ??/

A

albert stain

33
Q

L serum slop media indication time ??

34
Q

L s slop media what happening ??

A

small
circular
glistening
yellow tinge in 6-8 hrs

199

35
Q

Sterilization of L serum slop media ??

A

Glucose broth - Autoclaved
after adding serum ‘
inspissited at 80-85 * C
30 minutes for 3 days in serum inspissitor

36
Q

why cork screw bottle ?/

A

prevents contamination & dryness

37
Q

Type of media of C d?/

A

solid enriched

38
Q

composition of media of C d ?/

A

nutrient broth
glucose
serum - sheep / ox / horse

39
Q

pathogenic vs non-pathogenic by which test ?

A

eleks test

40
Q

what to do in pseudomembrane collitis emergency ?

A

Tracheostomy