Corynebacterium Flashcards
pathogenic corynebacterium name ??
C diptheriae
C renale
C pseudotuberculosis
C ulcerans
C haemolyticum
191
Non-pathogenic corynebacterium name ??
C acnes
C xerosis
C hoffmani
C pseuogenitalium
191
Types of corynebacterium ??
- gravis
mitis
intermediate
belfanti
191
Morphology of C d ??
- G + rod
- club shaped
shape of C d ??
pairly - V + L
in group - chinese letters
NON - character of C d ??
NON- spore + motile
191
Granules type of C d ?
metachromatic granules
culture media of C d ??
blood agar
\
blood tellurite agar
/
Loefflers serum slop media
characteristics of metachromatic granules ??
dye stain korle
cell - blue
grabules - red
191
why slop in media ??
to inc the surface area
easy access to collect specimen
easy observation
disease caused by C d»
respiratory / cutaneous Diptheria
192
pathogenecity of C d»_space;>
192 + 190
which C d produced Diptheria toxin ??
lysogenic strains of C d
`
clinical features of C d ??
- Pharyngitis
tonsilitis
sore throat
pseudomembrane
cervical adenitis + edema
Bull neck apperan
wHAT is bull neck appearance??
pseudomembranous pharyngitis + lymphadenopathy
193
2nd week complications of C d ??
Myocarditis
193
1st week complications of C d ??
extension of Pseduomembrane to the Larynx & trachea - Airway obstruction
193
3rd week complications of CD ??
Nerve weakness / paralysis
pralaysis - muscles of soft palate + pharynx - regurgitation of fluids in nose
enriched media of C d ?/
blood agar
chocolate agar
Loefflers serum slop media
Microscopic examination
Gram stainiung result ??
G + bacilli
chinese letter apperance
Albert stainign result of C d ??
Bacilli - blusih green
metachromatic granules - brick red
selective media for C d?/
K tellurite agar media
Tinsdale media - black colony
194
acute sore throat causing bacteria ??
C d - acute emergency
/
Streptococcus pyogens - long term
in-VIV0 toxigenicity test ?/
Animal inoculation test
194
in-VITRO toxigenicity test ??
PCR
\
ELISA
/
Eleks gel dissuision precipitin test
/
Immunochromographic
elecks test procedure ??
195
D vaccine name ??
D toxoid
197
How given ??
Pentavalent vaccine
Dose of vaccine ??
3 dose
6-10-14 weeks of age
who are called Diptheroids ?
Non-pathogenic species of C
198
Why chinese letter by C d ??`
due to incomplete seperation
sore throat cAUSING fungi ?/
candida
M/A of diptheria toxin ??
198
which stain demonstrate metachromatic granules ??/
albert stain
L serum slop media indication time ??
6-8 hours
L s slop media what happening ??
small
circular
glistening
yellow tinge in 6-8 hrs
199
Sterilization of L serum slop media ??
Glucose broth - Autoclaved
after adding serum ‘
inspissited at 80-85 * C
30 minutes for 3 days in serum inspissitor
why cork screw bottle ?/
prevents contamination & dryness
Type of media of C d?/
solid enriched
composition of media of C d ?/
nutrient broth
glucose
serum - sheep / ox / horse
pathogenic vs non-pathogenic by which test ?
eleks test
what to do in pseudomembrane collitis emergency ?
Tracheostomy