Uterine Pathology 3 Flashcards

Describe the spectrum of estrogen-driven endometrium from proliferative, hyperplastic to neoplastic progression.

1
Q

Compare simple endometrial hyperplasia to complex endometrial hyperplasia.

A
  • Simple endometrial hyperplasia (left)
    • increased gland and stroma ratio
    • diffusely disorganized glands
  • Complex endometrial hyperplasia (right)
    • significantly increased gland and stroma ratio
    • glandular crowding with complex and branching arrangement
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2
Q

What is the most important influence histologically with respect to the risk of progression to carcinoma?

A

cytological atypia

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3
Q

What is the estrogen-drive neoplastic progression in the endometrium?

A
  • Proliferative endometrium
  • Disordered endometrium
  • Simple hyperplasia
  • Complex hyperplasia
  • Adenocarcinoma endometroid
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