Gestational Trophoblastic Disease 6 Flashcards

Summarize the most important reasons for gestational trophoblastic neoplasia treatment success.

1
Q

What are the only true prognostic factors of survival in patients with metastatic GTN?

A
  • Number of metastases
  • Metastatic site other than lung/vagina
  • Previously failed chemotherapy
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2
Q

What are some success factors that contribute to GTN treatment?

A
  • Sensitivity to chemotherapy
  • HCG tumor marker
  • Referral to or consultation with specialized centers
  • Identification of prognostic factors
  • Chemotherapy, irradiation, surgery
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3
Q

What is involved in the surveillance after GTN?

A
  • HCG follow-up: weekly x 4, then monthly x 12
  • Contraception x 1 year
  • Ultrasound in first trimester of subsequent pregnancies
  • Histopathologic examination of products of contraception or placentas from future pregnancies
  • HCG 6 weeks after any pregnancy event
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