Endocrine Control Female Reproduction 2 Flashcards
Summarize the function of the hypothalamic-pituitary-ovarian axis.
1
Q
Describe the hypothalamic-pituitary-ovarian axis.
A
- Axis activated at menarche and continues until menopause
- Regulated by pulsatile GnRH, stimulates LH and FSH
- LH and FSH stimulates ovarian sex hormone production
- Estradiol and progesterone
- LH surge required for normal ovulation
2
Q
What are some regulators of GnRH pulse frequency.
A
- dopamine
- serotonin
- opioids
- GABA
- glutamate
- NPY
- norepinephrine
- corticotrophin releasing hormone (CRH)
- leptin