Endocrine Control Female Reproduction 2 Flashcards

Summarize the function of the hypothalamic-pituitary-ovarian axis.

1
Q

Describe the hypothalamic-pituitary-ovarian axis.

A
  • Axis activated at menarche and continues until menopause
  • Regulated by pulsatile GnRH, stimulates LH and FSH
  • LH and FSH stimulates ovarian sex hormone production
    • Estradiol and progesterone
    • LH surge required for normal ovulation
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2
Q

What are some regulators of GnRH pulse frequency.

A
  • dopamine
  • serotonin
  • opioids
  • GABA
  • glutamate
  • NPY
  • norepinephrine
  • corticotrophin releasing hormone (CRH)
  • leptin
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