Urinary System Flashcards

1
Q

Kidneys main function

A

maintain blood/body water homeostasis by the production of urine

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2
Q

How do kidneys monitor acid/base balance

A

excrete hydrogen ions during acidosis

excrete bicarbonate ions during alkalosis

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3
Q

How do kidneys raise blood pressure

A

secrete renin and erythropoietin which accelerates red blood cell production

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4
Q

What is the function of the ureters

A

conduct urine to the bladder where it is stored

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5
Q

Where are the kidneys

A

posterior to the abdominal wall, high up, under the diaphragm.

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6
Q

How are they enclosed

A

retroperitoneal (behing peritoneum)

encapsulated and protected by layers of fascia and fairly firm renal fat

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7
Q

The medulla is made up of Renal pyramids, What are renal pyramids?

A

They house the nephrons with their function of filtration and reabsorption

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8
Q

What do the pyramids consist of

A

mainly of tubules that transport urine from the outer part of the kidney where urine is produced
to the minor calyces (which converge on major calyces), or cup-shaped cavities in which urine collects before it passes through the ureter to the bladder.

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9
Q

cortex

A

between capsule and medulla houses blood vessels and nephrons

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10
Q

State the order of nephron structure

A
renal corpuscle (glomerulus) = network of blood supply
Proximal convoluted tubule 
loop of henle
Distal convoluted tubule 
Collecting duct
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11
Q

Two types of nephron: Juxtamedullary

A

Receive ~ 10% renal supply
• Designed to concentrate urine
• Glomeruli in inner cortical regions; long nephron loops.
• Associated with vasa recta ie vascular structure.

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12
Q

Superficial

A

• Receive ~ 90% renal supply
• Reabsorb large % of fluid that
filters from vasculature.
• Glomeruli in outer cortical regions; short nephron loops.

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13
Q

Tell me about the position of the ureter

A

passes posterior to the ovary

passes lateral to cervix and vagina

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14
Q

Tell me about the filling of the bladder

A

Walls are muscular
peristaltic waves propel urine down the ureter
bladder fills by relaxation of its muscular wall (detrusor muscle)

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15
Q

tell me about the emptying of the bladder

A

muscular contraction, aided by raised inter abdominal pressure

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16
Q

Tell me about the external sphincter

A

around urethra is striated and under voluntary control

17
Q

What does the kidney control

A

blood pressure
tissue osmolality
electrolyte levels

18
Q

What does the nephron comprise of

A

comprises a blood filtration part (glomerulus) and a filtrate recovery part (renal tubule)

19
Q

how is blood filtered

A

through a glomerular filtration barrier to separate plasma from cells and proteins

20
Q

What is the role of the proximal tubule

A

recovers 2/3 of fluid and up to 100% of solutes that are filtered into renal tubule by the glomerulus

21
Q

Tell me about PT epithelial cells

A

they have apical microvilli that increase surface area and junctions between cells and are leaky to maximise free flow of water and dissolved solutes

22
Q

What drives Na reabsorption in the PT

A

basolateral Na-K ATPase through cotransport with organic solutes and in exchange H+

23
Q

Where does Cl+ absorption occur

A

late Proximal tubule by paracellular route or by a Cl- base exchanger

24
Q

What drives water absorption

A

osmosis

influx of Na Cl and solutes

25
Q

Where is this fluid returned to

A

the vasculature via peritubular network

26
Q

What is bladder capacity

A

500ml

27
Q

What does a reflex cause

A

parasympathetic motor efferents to stimulate bladder contraction

28
Q

What prevents emptying of the bladder

A

CNS until peter sphincter is relaxed voluntarily

29
Q

What is micro nutrition

A

urinating