immunology Flashcards
What is the Innate defence mechanism
first line of defence
not improved by further exposure
What is the adaptive defence mechanism
second line of defence
improved by further exposure
What happens when the boys barriers are breached
attempt to contain and localise
-phagocytes
neutrophils monocytes/macrophage lineage
What are the four types of chemicals
acute phase proteins
complement proteins
interferons
cytokines
What is an opsonin
substance that coats ell/bacteria and enhances the ability of phagocytes to phagocytose the particle
OPSONIZATION IS THE PROCESS
What are the three complement functions
lysis (rupture cell wall leading to degradation)
chemotaxis
opsonisation
What is an important complement opsonin
C3b
What stimulates IgE and IgA in pregnancy
oestrogen production
wants to do this as oestrogen inhibits T-cells from rejecting the foetus
Autoimmunity (autoimmune disease)
response can be antibody or cell mediated, immune system reacting to self loss of tolerance