immunology Flashcards

1
Q

What is the Innate defence mechanism

A

first line of defence

not improved by further exposure

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2
Q

What is the adaptive defence mechanism

A

second line of defence

improved by further exposure

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3
Q

What happens when the boys barriers are breached

A

attempt to contain and localise
-phagocytes
neutrophils monocytes/macrophage lineage

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4
Q

What are the four types of chemicals

A

acute phase proteins
complement proteins
interferons
cytokines

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5
Q

What is an opsonin

A

substance that coats ell/bacteria and enhances the ability of phagocytes to phagocytose the particle
OPSONIZATION IS THE PROCESS

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6
Q

What are the three complement functions

A

lysis (rupture cell wall leading to degradation)
chemotaxis
opsonisation

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7
Q

What is an important complement opsonin

A

C3b

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8
Q

What stimulates IgE and IgA in pregnancy

A

oestrogen production

wants to do this as oestrogen inhibits T-cells from rejecting the foetus

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9
Q

Autoimmunity (autoimmune disease)

A

response can be antibody or cell mediated, immune system reacting to self loss of tolerance

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